Ophiorrhiza, a promising herbaceous source of the anticancer compound camptothecin
DOI:
https://doi.org/10.14719/pst.2020.7.2.660Keywords:
medicinal value, traditional uses, biological activities, bioproductionAbstract
Camptothecin is an important source for the synthesis of some of the major anti-cancer agents such as irinotecan and topotecan. Traditional source of camptothecin are prominently woody plants such as Camptotheca acuminata Decne. and Nothopodytes nimmoniana (Graham) Mabb., and the increasing demand for camptothecin leads to the level of threatening their existence. Ophiorrhiza species composed of herbaceous plants with quick growth characteristics which are reported as alternative source of camptothecin. The present review focus on taxonomical status, traditional uses, biological activities and phytochemical constituents with a special attention in bioproduction of camptothecin from Ophiorrhiza species and its future prospects.
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Krishnakumar G, Dintu KP, Varghese SC, Nair DS, Gopinath G, Rameshkumar KB, Satheeshkumar K, Krishnan PN. Ophiorrhiza, a promising herbaceous source of the anticancer compound camptothecin. Plant Sci. Today [Internet]. 2020 May 2 [cited 2024 Apr. 25];7(2):240-5. Available from: https://horizonepublishing.com/journals/index.php/PST/article/view/660
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