A review on chemical profiles and biological activities of essential oil from some plants belonging to family Scrophulariaceae

Authors

  • Thao Nguyen Luu Institute of Biotechnology and Food Technology, Industrial University of Ho Chi Minh City, No. 12 Nguyen Van Bao, Ward 4, Go Vap District, Ho Chi Minh City, Vietnam https://orcid.org/0000-0002-8146-1102
  • Hong Thien Van Institute of Biotechnology and Food Technology, Industrial University of Ho Chi Minh City, No. 12 Nguyen Van Bao, Ward 4, Go Vap District, Ho Chi Minh City, Vietnam https://orcid.org/0000-0003-0151-5068

DOI:

https://doi.org/10.14719/pst.1594

Keywords:

Biological activity, Chemical components, Essential oil, Scrophulariaceae

Abstract

Scrophulariaceae is a large family, many species of which have been reported to have a wide range of biological activities and uses as folk medicines. The essential oils from species belonging to this family mainly contain monoterpene hydrocarbons, oxygenated monoterpenes, sesquiterpene hydrocarbons, oxygenated sesquiterpenes and non-terpenes. Furthermore, their essential oils have been reported to have a variety of biological activities such as antimicrobial, antioxidant, insecticidal etc. The objective of this review is to provide a brief overview of the chemical composition and biological activities of the essential oils isolated from different parts of species included in the Scrophulariaceae family. In addition, this paper also introduces the therapeutic potentials and provides the evidence for future medicinal applications of those species.

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References

Silva NCC, Fernandes JA. Biological properties of medicinal plants: a review of their antimicrobial activity. The Journal of Venomous Animals and Toxins including Tropical Diseases. 2010;16(3):402-13. https://doi.org/10.1590/S1678-91992010000300006

Hemraj V, Anil J. Antimicrobial activities of medicinal plants-review. International Journal of Research in Pharmaceutical and Biomedical Sciences. 2012;3(1):222-30.

Marwa A, Abdelrhman A. Chemical diversity of essential oils from flowers, leaves and stems of Rhanterium epapposum Oliv. growing in northern border region of Saudi Arabia. Asian Pacific Journal of Tropical Biomedicine. 2016;6(9):767-70. https://doi.org/10.1016/j.apjtb.2016.07.010

Mahesh B, Satish S. Antimicrobial activity of some important medicinal plant against plant and human pathogens. World Journal of Agricultural sciences. 2008;4:839-43.

Brahmachari G. Limnophila (Scrophulariaceae): Chemical and pharmaceutical aspects - an update. The Open Natural Products Journal. 2014;7(1):1-14. https://doi.org/10.2174/1874848101407010001

Pasdaran A, Hamedi A. The genus Scrophularia: a source of iridoids and terpenoids with a diverse biological activity. Pharmaceutical biology. 2017;55(1):2211-33. https://doi.org/10.1080/13880209.2017.1397178

Roy R, Jash SK, Singh RK, Gorai D. Limnophila (Scrophulariaceae): chemical and pharmacological aspects. World Journal of Pharmaceutical Research. 2015;4(7):1269-300.

Hamid AA, Aiyelaagbe OO, Usman LA. Essential oils: its medicinal and pharmacological uses. International Journal of Current Research. 2011;33(2):86-98.

Neiro L, Olivero J, Stashenko E. Repellent activity of essential oils: a review. Bioresource Technology. 2010;101(1):372-78. https://doi.org/10.1016/j.biortech.2009.07.048

Glicerio LM, Nerlis PC, Enilson PC, Miladys TA, Adriana HB. Essential oils as a source of bioactive molecules. Rev Colomb Cienc Quím Farm. 2019;48(1):80-93. https://doi.org/10.15446/rcciquifa.v48n1.80067

Kim SR, Lee KY, Koo KA, Sung SH, Lee NG, Kim J, Kim YC. Four new neuroprotective iridoid glycosides from Scrophularia buergeriana Roots. J Nat Prod. 2002;65(11):1696-99. https://doi.org/10.1021/np0202172

Roodsari R, Zamanian Azodi M, Salimpour F. Herbal remedies and medicines; introducing some Iranian plants. Journal of Paramedical Sciences. 2013;4(2):116-22.

Sohn SH, Ko E, Jeon SB, Lee BJ, Kim SH, Dong MS et al. The genomewide expression profile of Scrophularia ningpoensis-treated thapsigargin-stimulated U-87MG cells. Neurotoxicology. 2009;30(3):368-76. https://doi.org/10.1016/j.neuro.2009.02.006

Esposito E, Dal TR, Pressi G, Bramanti P, Meli R, Cuzzocrea S. Protective effect of verbascoside in activated C6 glioma cells: possible molecular mechanisms. Naunyn-Schmied Arch Pharmacol. 2010;381:93-105. https://doi.org/10.1007/s00210-009-0466-0

Adewusi EA, Moodley N, Steenkamp V. Antioxidant and acetylcholinesterase inhibitory activity of selected southern African medicinal plants. South African Journal of Botany. 2011;77(3):638-44. https://doi.org/10.1016/j.sajb.2010.12.009

Oh WJ, Jung U, Eom HS, Shin HJ, Park HR. Inhibition of lipopolysaccharide-induced proinflammatory responses by Buddleja offcinalis extract in BV-2 microglial cells via negative regulation of NF-?B and ERK1/2 signaling. Molecules. 2013;18(8):9195-9206. https://doi.org/10.3390/molecules18089195

Pendota SC, Aderogba MA, Ndhlala AR, Van SJ. Antimicrobial and acetylcholinesterase inhibitory activities of Buddleja salviifolia (L.) Lam. leaf extracts and isolated compounds. J Ethnopharmacol. 2013;148(2):515-20. https://doi.org/10.1016/j.jep.2013.04.047

Nguyen TL, Le NT. Study of the essential oil of Limnophila rugosa (Roth.) Merr. in the South of Vietnam. Journal of Essential Oil Bearing Plants. 2011;14(3):366-72. https://doi.org/10.1080/0972060X.2011.10643947

Van HT, Do TT, Luu TN, Le VS, Doan VD. Chemical constituents and antibacterial activities of essential oils from aerial parts of three Limnophila species (Scrophulariaceae) in Southern Vietnam. Research Journal of Chemistry and Environment. 2021;25(4):12-19.

Verma RS, Padaliaa RC, Chauhan A. Geographical impact on essential oil composition of Limnophila rugosa (Roth.) Merr. Journal of Essential Oil Research. 2014;26(5):338-41. https://doi.org/10.1080/10412905.2014.922510

Do ND, Tran DT, Tran HT, Ogunwande IA. Chemical constituents of leaf essential oils of four Scrophulariaceae species grown in Vietnam. Journal of Essential Oil Research. 2015. https://doi.org/10.1080/10412905.2015.1067650

Costa RG, Faria LJG, Gusmao SAL , Silva JKR, Andrade EHA, Maia JGS. Essential oil of pataqueira (Conobea scoparioides Benth.): from natural occurrence and produced by hydroponics. Advances in Plants and Agriculture Research. 2014;1(3):90-94. http://doi.org/10.15406/apar.2014.01.00015

Pasdaran A, Delazar A, Nazemiyeh H, Nahar L, Sarker SD. Chemical composition and antibacterial (against Staphylococcus aureus) and free-radical-scavenging activities of the essential oil of Scrophularia amplexicaulis Benth. Rec Nat Prod. 2012;6(4):350-55.

Asgharian P, Afshar FH, Asnaashari S, Moghaddam SB, Ebrahimi A, Delazar A. Characterization of terpenoids in the essential oil extracted from the aerial parts of Scrophularia subaphylla growing in Iran. Advanced Pharmaceutical Bulletin. 2015;5(4):557-61. http://doi.org/10.15171/apb.2015.075

Asgharian P, Afshar FH, Asnaashari S, Moghaddam SB, Delazar A. The seasonal variations of the chemical composition of essential oil obtained from Scrophularia frigida. Jundishapur Journal of Natural Pharmaceutical Products. 2016;11(1):29742. http://doi.org/10.17795/ jjnpp-29742

Nguyen XD, Le VH, Leclercq PA. A new chemotype of Adenosma glutinosum (L.) Druce var. caeruleum (R.Br.) Tsoong from Vietnam. Journal of Essential Oil Research. 1996;8:359-62. https://doi.org/10.1080/10412905.1996.9700640

Bhuiyan MNI, Akter F, Chowdhury JU, Begum J. Chemical constituents of essential oils from aerial parts of Adenosma capitatum and Limnophila aromatica. Bangladesh J Pharmacol. 2010;5:13-16. https://doi.org/10.3329/bjp.v5i1.4019

Zeng Z, Meng C, Ye X, Zeng Z. Analysis of volatile components of

Adenosma indianum (Lour.) Merr. by steam distillation and headspace solid-phase microextraction. Journal of Chemistry. 2013;545760. https://doi.org/10.1155/2013/545760

Sadgrove NJ, Hitchcock M, Watson K, Jones GL. Chemical and biological characterization of novel essential oils from Eremophila bignoniiflora (F. Muell) (Myoporaceae): A traditional aboriginal Australian bush medicine. Phytotherapy Research. 2013;27:1508-16. http://doi.org/10.1002 / ptr.4889

Sadgrove NJ, Mijajlovic S, Tucker DJ, Watson K, Jones GL. Characterization and bioactivity of essential oils from novel chemotypes of Eremophila longifolia (F. Muell) (Myoporaceae): a highly valued traditional Australian Medicine. Flavour Fragr J. 2011;26:341-50. https://doi.org/10.1002/ffj.2062

Thanatuskitti P, Siripornpanich V, Sayorwan W, Palanuve C, Ruangrungsi N. The effects of inhaled Limnophila aromatica essential oil on brain wave activities and emotional states in healthy volunteers: a randomized crossover study. Research Journal of Pharmacognosy. 2020;7(4):1-9. https://dx.doi.org/10.22127/rjp.2020.230400.1586

Mardani M, Rezapour S, Eftekhari Z, Majid AS, Rashidipour M, Afsordeh O et al. Chemical composition of Scrophularia deserti. International Journal of Pharm. Tech Research. 2016;9(6):285-90. http://doi.org/10.13040/IJPSR.0975-8232.8 (5).1953-58

Sadgrove NJ, Jones GL. Cytogeography of essential oil chemotypes of Eremophila longifolia F. Muell (Scrophulariaceae). Phytochemistry. 2014. https://doi.org/10.1016/j.phytochem.2014.05.005

Souza LGS, Almeida MCS, Monte FJQ, Santiago GMP, Braz-Filho R, Lemos TLG. Constituintes químicos de Capraria bi?ora (Scrophulariaceae) e atividade larvicida de seu óleo essencial. Quim Nova. 2012;35(11):2258-62. https://doi.org/10.1590/S0100-40422012001100032

Mammen D, Daniel M. Volatile oils and flavones of Stemodia viscosa Roxb. Journal of Advanced Pharmacy Education and Research. 2012;2(4):221-24.

Arriaga AMC, Rodrigues FEA, Lemos TLG, Oliveira MCF, Lima JQ, Santiago GMP, Raimundo BF, Mafezoli J. Composition and larvicidal activity of essential oil from Stemodia maritima L. Natural Product Communications. 2007;2(12):1237-39. https://doi.org/10.1177%2F1934578X0700201209

Kaya AA, Ucuncu O, Ilter SM, Baltaci C, Ozturk S. Chemical composition and bioactive properties of the essential oil of Rhinanthus angustifolius subsp. grandiflora. Bulgarian Chemical Communications. 2017;49(4):923-27.

Silva WMB, Assunção JCC, Araújo RM, Silveira ER, Pessoa ODL. New volatile constituents from leaves of Stemodia trifoliata (Link.) Reichb. (Schrophulariaceae). J Braz Chem Soc. 2009;20(1):37-41. https://doi.org/10.1590/S0103-50532009000100007

Oliveira LLDSS, Rocha MKL, Oliveira JCS, Camara CAG. Chemical composition of essential oil from leaves of Stemodia foliosa growing wild in a fragment of the atlantic forest of Pernambuco, Brazil. Chemistry of Natural Compounds. 2018;54(5):1000-01. https://doi.org/10.1007/s10600-018-2534-5

Novy P, Davidova H, Cecilia SSR, Rondevaldova J, Pulkrabek J, Kokoska L. Composition and antimicrobial activity of Euphrasia rostkoviana Hayne essential oil. Evidence-Based Complementary and Alternative Medicine Volume. 2015. https://doi.org/10.1155/2015/734101

Nikkhah E, Asnaashari S, Babaei H, Afshar FH, Delazar A. Chemical composition and biological activities of essential oil and methanol extract of Scrophularia umbrosa. Research Journal of Pharmacognosy. 2017;4(1):41-50.

Rend AG, Kalayci Y, Korkmaz B, Karaoglu SA, Yayh N. Chemical composition and antimicrobial activity of the essential oils of five Scrophularia L. species from Turkey. Records of Natural Products. 2017;11(6):521-31. http://doi.org/10.25135/rnp.67.17.02.010

Maia JGS,¬ Zoghbi MGB, Andrade EHA. Silva MHL, Essential oils from Conobea scoparioides (Cham. & Schltdl.) Benth. Flavour and Fragrance Journal. 2000;15:413-14. https://doi.org/10.1002/1099-1026(200011/12)15:6<413::AID-FFJ931>3.0.CO;2-H

Arunya S, Nuntavan B, Opa V, Hiroshi W. Antioxidant activity of Limnophila aromatica Merr. Thai J Phytopharm. 2004;11:11-17.

Thongdon J, Inprakhon AP. Composition and biological activities of essential oils from Limnophila geoffrayi Bonati. World Journal of Microbiology and Biotechnology. 2009;25:1313-20. https://doi.org/10.1007/s11274-009-0016-4

Barati A, Sani AM. Chemical composition of the essential oil and antimicrobial activity of aqueous and methanolic extracts of Scrophularia khorassanica. Journal of Essential Oil Bearing Plants. 2017;20(3):662-71. https://doi.org/10.1080/0972060X.2017.1329668

Bahrami S, Jalali MHR, Ramezani Z, Janeh G. Anti-leishmanial activity and identification of chemical constituents of Scrophularia striata essential oil by head space solid phase micro extraction gas chromatography mass spectrometry (HS-SPME GC-MS). Boletín latinoamericano y del caribe de plantas medicinales y aromáticas. 2019;18(6):586-94.

Miller AB, Cates RG, Lawrence M, Soria AF, Espinoza LV, Martinez JV, Arbizú DA. The antibacterial and antifungal activity of essential oils extracted from Guatemalan medicinal plants. Pharmaceutical Biology. 2015;53(4):548-54. https://doi.org/10.3109/13880209.2014.932391

Mendonça FAC, Silva KFS, Santos KK, Ribeiro Júnior KAL, Sant’Ana AEG. Activities of some Brazilian plants against larvae of the mosquito Aedes aegypti. Fitoterapia. 2005;76:629-36. https://doi.org/10.1016/j.fitote.2005.06.013

Santiago GMP, Lemos TLG, Pessoa ODL, Arriaga AMC, Matos FJA, Lima MAS et al. Larvicidal actvity against Aedes aegypti L. (Díptera: Culicidae) of essential oils of Lippia species from Brazil. Natural Product Communications. 2006;1:573-76. https://doi.org/10.1177/1934578X0600100711

Santos RP, Nunes EP, Nascimento RF, Santiago GMP, Menezes GHA, Silveira ER, Pessoa OD. Chemical composition and larvicidal activity of the essential oils of Cordia leucomalloides and Cordia curassavica from the Northeast of Brazil. Journal of Brazilian Chemical Society. 2006;17:1027-30. https://doi.org/10.1590/S0103-50532006000500030

Yu JQ, Liao ZX, Cai XQ, Lei JC, Zou GL. Composition, antimicrobial activity and cytotoxicity of essential oils from Aristolochia mollissima. Environmental Toxicology and Pharmacology. 2007;23:162-67. https://doi.org/10.1016/j.etap.2006.08.004

Murugan K, Murugan P, Noortheen A. Larvicidal and repellent potential of Albizzia amara Boivin and Ocimum basilicum Linn. against dengue vector, Aedes aegypti (Insecta: Díptera: Culicidae). Bioresource Technology. 2007;98:198-201. https://doi.org/10.1016/j.biortech.2005.12.009

Tammannavar P, Pushpalatha C, Jain S, Sowmya SV. An unexpected positive hypersensitive reaction to eugenol. Case Rep. 2013;bcr2013009464. https://doi.org/10.1136/bcr-2013-009464

Marchese A, Barbieri R, Coppo E, Orhan IE, Daglia M, Nabavi SF et al. Antimicrobial activity of eugenol and essential oils containing eugenol: A mechanistic viewpoint. Crit Rev Microbiol. 2017;43: 668-89. https://doi.org/10.1080/1040841X.2017.1295225

Devi KP, Nisha SA, Sakthivel R, Pandian SK. Eugenol (an essential oil of clove) acts as an antibacterial agent against Salmonella typhi by disrupting the cellular membrane. J. Ethnopharmacol. 2010;130:107-15. https://doi.org/10.1016/j.jep.2010.04.025

Ulanowska M, Olas B. Biological Properties and Prospects for the Application of Eugenol-A Review. Int J Mol Sci. 2021;22:3671. https://doi.org/10.3390/ijms22073671

Mak KK, Kamal MB, Ayuba SB, Sakirolla R, Kang YB, Mohandas K et al. A comprehensive review on eugenol’s antimicrobial properties and industry applications: A transformation from ethnomedicine to industry. Phcog Rev. 2019;13:1-9. https://doi.org/10.4103/phrev.phrev_46_18

Kabuto H, Tada M, Kohno M. Eugenol [2-Methoxy-4-(2-propenyl)phenol] prevents 6-hydroxydopamine induced dopamine depression and lipid peroxidation inductivity in mouse striatum. Biol Pharm Bull. 2007;30:423-27. https://doi.org/10.1248/bpb.30.423

Khalil AA, Rahman U, Khan MR, Sahar A, Mehmood T, Khan M. Essential oil eugenol: sources, extraction techniques and nutraceutical perspectives. RSC Adv. 2017;7:32669-81. https://doi.org/10.1039/C7RA04803C

Pavithra B. Eugenol-A Review. J Pharm Sci Res. 2014;6:153-54.

Gülçin I. Antioxidant activity of eugenol: A structure-activity relationship study. J Med Food. 2011;14:975-85. https://doi.org/10.1089/jmf.2010.0197

Dahham SS, TabanaYM, Iqbal MA, Ahamed OBK, Ezzat MO, Majid ASA. The anticancer, antioxidant and antimicrobial properties of the sesquiterpene ?-caryophyllene from the essential oil of Aquilaria crassna. Molecules. 2015;20:11808-29. https://doi.org/10.3390/molecules200711808.

Santos GKN, Dutra KA, Barros RA, Camara CAG, Lira DD, Gusmao NB. Essential oils from Alpinia purpurata (Zingiberaceae): Chemical composition, oviposition deterrence, larvicidal and antibacterial activity. Ind Crops Prod. 2012;40:254-60. https://doi.org/10.1016/j.indcrop.2012.03.020

Lis-Balchin M, Ochocka RJ, Deans SG, Asztemborska M, Hart S. Bioactivity of the enantiomers of limonene. Med Sci Res. 1996;24:309-10.

Guimarães AC, Meireles LM, Lemos MF, Guimarães MCC, Endringer DC, Fronza M, Scherer R. Antibacterial activity of terpenes and terpenoids present in essential oils. Molecules. 2019;24:2471. https://doi.org/10.3390/molecules24132471

Prudent D, Perineau F, Bessiere JM, Michel G, Bravo R. Chemical analysis, bacteriostatic and fungistatic properties of the essential oil of the atoumau from martinique (Alpinia speciosa K. schum.). J Essent Oil Res. 1993;5:255-64. https://doi.org/10.1080/10412905.1993.9698218

Leite AM, Lima EO, Souza EL, Diniz MFFM, Trajano VN, Medeiros IA. Inhibitory effect of ?-pinene, ?-pinene and eugenol on the growth of potential infectious endocarditis causing Gram-positive bacteria. Braz J Pharm Sci. 2007;43:122-26. https://doi.org/10.1590/S1516-93322007000100015

Rivas ACS, Lopes PM, Barros MMA, Machado DCC, Alviano CS, Alviano DS. Biological activities of ?-pinene and ?-pinene enantiomers. Molecules. 2012;17:6305-16. https://doi.org/10.3390/molecules17066305

Moghaddam M, Alymanesh MR, Mehdizadeh L, Mirzaei H, Pirbalouti AG. Chemical composition and antibacterial activity of essential oil of Ocimum ciliatum, as a new source of methyl chavicol, against ten phytopathogens. Industrial Crops and Products. 2014;59:144-48. https://doi.org/10.1016/j.indcrop.2014.05.006

Bouvier-Brown NC, Goldstein AH, Worton DR, Matross DM, Gilman JB, Kuster WC, Welsh-Bon D, Warneke C, Gouw JA, Cahill TM, Holzinger R. Methyl chavicol: characterization of its biogenic emission rate, abundance and oxidation products in the atmosphere. Atmos Chem Phys. 2009;9:2061-74. https://doi.org/10.5194/acp-9-2061-2009

Mohanapriya S, Muthukumaran, Vairam S. Synthesis, characterization, thermal behavior and antimicrobial activity of 3-methyl benzoate complexes of transition metal with hydrazine. Bull Chem Soc Ethiop. 2016;30(2):241-52. http://dx.doi.org/10.4314/bcse.v30i2.8

Thakre AD, Mulange SV, Kodgire SS, Zore GB, Karuppayil SM. Effects of cinnamaldehyde, ocimene, camphene, curcumin and farnesene on Candida albicans. Advances in Microbiology. 2016;6:627-43. http://dx.doi.org/10.4236/aim.2016.69062

Published

11-05-2022 — Updated on 01-07-2022

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Luu TN, Van HT. A review on chemical profiles and biological activities of essential oil from some plants belonging to family Scrophulariaceae. Plant Sci. Today [Internet]. 2022 Jul. 1 [cited 2024 Nov. 21];9(3):610-7. Available from: https://horizonepublishing.com/journals/index.php/PST/article/view/1594

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