Antimicrobial activity of leaf and root methanolic extracts from Vinca pusilla Murr.

Authors

  • Gireesh Ankad Regional Medical Research Centre, ICMR, Nehru Nagar, Belagavi
  • Harsha Pednekar Regional Medical Research Centre, ICMR, Nehru Nagar, Belagavi
  • Sandeep R Pai Regional Medical Research Centre, ICMR, Nehru Nagar, Belagavi http://orcid.org/0000-0002-1133-8061
  • Harsha Hegde Regional Medical Research Centre, ICMR, Nehru Nagar, Belagavi, Karnataka, India
  • Subarna Roy Regional Medical Research Centre, ICMR, Nehru Nagar, Belagavi
  • S Hoti Regional Medical Research Centre, ICMR, Nehru Nagar, Belagavi, Karnataka

DOI:

https://doi.org/10.14719/pst.2016.3.1.163

Keywords:

Vinca pusilla, traditional medicine, methanolic extract, antimicrobial, Bacillus subtilis, Staphylococcus aureus

Abstract

Vinca pusilla Murr. is a traditional medicinal plant used to treat several diseases. To substantiate the traditional medicinal utility of the plant, the present study aims at screening the antimicrobial activity of methanolic extracts of leaves and roots against five Gram positive, five Gram negative bacterial and four fungal strains. The minimum inhibitory concentration (MIC) were determined by two fold dilution assay. The results indicated that, leaf and root extracts were more effective on Bacillus subtilis and Staphylococcus aureus strains (MIC < 1 mg/mL). The tested organisms were sensitive to root extract compared to leaf extract. Fungal strains were resistant than the bacterial strains to both the extracts. Thus the present study illustrates the antimicrobial potential of the plant. 

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Author Biographies

Gireesh Ankad, Regional Medical Research Centre, ICMR, Nehru Nagar, Belagavi

Scientist, Herbal Medicine Div (Bio Medical informatics Centre)

Harsha Pednekar, Regional Medical Research Centre, ICMR, Nehru Nagar, Belagavi

Research Scholar,

Sandeep R Pai, Regional Medical Research Centre, ICMR, Nehru Nagar, Belagavi

Scientist, Plant Biotech Div

Harsha Hegde, Regional Medical Research Centre, ICMR, Nehru Nagar, Belagavi, Karnataka, India

Scientist 'C'

Herbal Medicine Division (Biomedical Informatics Centre), Plant biotechnology and Tissue culture Division, Ethnomedicine Division

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Published

01-01-2016

How to Cite

1.
Ankad G, Pednekar H, Pai SR, Hegde H, Roy S, Hoti S. Antimicrobial activity of leaf and root methanolic extracts from Vinca pusilla Murr. Plant Sci. Today [Internet]. 2016 Jan. 1 [cited 2024 Nov. 21];3(1):6-8. Available from: https://horizonepublishing.com/journals/index.php/PST/article/view/163

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Section

Research communications

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