Chemical profiles and antibacterial activity of acetone extract of two Curcuma species from Vietnam
DOI:
https://doi.org/10.14719/pst.1993Keywords:
Curcuma thorelii, Curcuma cotuana, GC/MS, Chemical composition, Antibacterial activityAbstract
Curcuma thorelii Gagnep. and Curcuma cotuana Luu, Škorni?k. & H.?.Tr?n are the rare species only found in Southeast Asia. The present study was the first to explore the chemical compositions and antibacterial effects of the whole plant acetone extracts of these 2 species. Altogether 41 and 31 compounds have been identified in C. thorelii and C. cotuana extracts by gas chromatography/mass spectrometry. Accordingly, the C. thorelii extract contained (E)-labda-8(17),12-diene-15,16-dial (33.37%), vitamin E (12.33%), phytol (9.83%) as the major compounds while C. cotuana extract contained predominantly (E)-labda-8(17),12-diene-15,16-dial (14.58%), n-hexadecanoic acid (10.96%), 3,7,11,15-tetramethylhexadec-2-en-1-yl acetate (8.13%), ?-sitosterol (7.97%). In addition, results from disc diffusion assay have shown that C. thorelii acetone extract had inhibitory effects on 5 out of 10 pathogenic bacterial strains such as Bacillus cereus (ATCC 11778), Listeria monocytogenes (ATCC 19111), Staphylococcus aureus (ATCC 25923), S. aureus (ATCC 29213) and S. saprophyticus (BAA750) while C. cotuana acetone extract was found to be effective only against B. cereus. The obtained results showed that the acetone extracts of C. thorelii and C. cotuana possessed several valuable bioactive compounds as well as promising antibacterial activity, which place a good foundation for future pharmaceutical product development.
Downloads
References
Rahaman M, Rakib A, Mitra S, Tareq A, Emran T, Shahid-Ud-Daula A et al. The Genus Curcuma and Inflammation: Overview of the Pharmacological Perspectives. Plants 2021;63(10):2020. https://doi.org/10.3390/plants10010063
Leong-Škorni?ková J, Ly NS, Nguyen QB. Curcuma arida and C. sahuynhensis, 2 new species from subgenus Ecomata (Zingiberaceae) from Vietnam. Phytotaxa. 2015;192(3):181-9. https://doi.org/10.11646/phytotaxa.192.3.4
Pham HH. An Illustrated Flora of Vietnam. Vol. 3. Araceae. Young Publishing House, Ho Chi Minh City; 2000.
Nguyen QB. Zingiberaceae-Flora of Vietnam. Science and Technology Publishing, Ha Noi; 2017.
Akarchariya N, Sirilun S, Julsrigival J, Chansakaowa S. Chemical profiling and antimicrobial activity of essential oil from Curcuma aeruginosa Roxb., Curcuma glans K. Larsen & J. Mood and Curcuma cf. xanthorrhiza Roxb. collected in Thailand. Asian Pacific Journal of Tropical Biomedicine. 2017;7(10):881-85. https://doi.org/10.1016/j.apjtb.2017.-09.009
Rukayadi Y, Hwang JK. In vitro activity of xanthorrhizol isolated from the rhizome of Javanese turmeric (Curcuma xanthorrhiza Roxb.) against Candida albicans biofilms. Phytotherapy Research. 2013;27(7):1061-66. https://doi.org/10.1002/ptr.4834
Udin Z. Sitotoksisitas Xanthorrhizol Dari Minyak Atsiri Rimpang Curcuma Xanthorrhiza Roxb. Terhadap Sel Kanker Payudara YBM-1. Jurnal Kimia Terapan Indonesia. 2013;15(1):23-19. https://doi.org/10.14203/jkti.v15i1.101
Araujo C, Leon L. Biological activities of Curcuma longa L. Memórias do Instituto Oswaldo Cruz. 2001;96:723-28. https://doi.org/10.1590/S0074-02762001000500026
Van HT, Phan UTX, Doan VD, Le VS. Chemical Constituents of Essential Oil from Rhizomes and Aerial Parts of Curcuma gracillima. Chemistry of Natural Compounds. 2021;57(3):569-71. https://doi.org/10.1007/s10600-021-03419-6
Azeez TB, Lunghar J. Antiinflammatory effects of Turmeric (Curcuma longa) and Ginger (Zingiber officinale). Inflammation and Natural Products. 2021:127-46. https://doi.org/10.1016/B978-0-12-819218-4.00011-0
Leong?Škorni?ková J, Šída O, Tran HD. Curcuma pygmaea sp. nov. (Zingiberaceae) from Vietnam and notes on two related species C. parviflora and C. thorelii. Nordic Journal of Botany. 2014;32(1):119-27. https://doi.org/10.1111/njb.91749
Luu HT, Tran HD, Nguyen TQT, Leong?Škorni?ková J. Curcuma cotuana sp. nov. (Zingiberaceae: Zingibereae) from central Vietnam. Nordic Journal of Botany. 2017;35(5):-552-56. https://doi.org/10.1111/njb.01594
Van HT, Luu LT, Pham TV, Tran MD, Nguyen TKN, Le VS, Nguyen QH, Le TT, Nguyen PN. Chemical constituents and antibacterial activity of essential oils of Curcuma thorelii Gagnep. (Zingiberaceae). Chem Nat Compd. 2022 (In press).
Le HT, Luu TN, Nguyen HMT, Nguyen DH, Le PTQ, Trinh NN et al. Antibacterial, antioxidant and cytotoxic activities of different fractions of acetone extract from flowers of Dipterocarpus intricatus Dyer. (Dipterocarpaceae). Plant Science Today. 2021;8(2):273-77. https://doi.org/0.14719/pst.2021.8.2.1086
Van HT, Le NT, Nguyen DL, Tran GB, Huynh NTA, Vo HS et al. Chemical profile and antibacterial activity of acetone extract of Homalomena cochinchinensis Engl. (Araceae). Plant Science Today. 2021;8(1):58-65. https://doi.org/10.14719/pst.2021.8.1.971
Clinical, Institute LS. Methods for antimicrobial dilution and disk susceptibility testing of infrequently isolated or fastidious bacteria; approved guideline. Clinical and Laboratory Standards Institute Wayne, PA; 2010.
Lognay G, Marlier M, Severin M, Haubruge E, Gibon V, Trevejo E. On the characterization of some terpenes from Renealmia alpinia Rott. (Maas) oleoresin. Flavour and Fragrance Journal. 1991;6(1):87-91. https://doi.org/10.1002/ffj.2730060113
Itokawa H, Morita M, Mihashi S. Phenolic compounds from the rhizomes of Alpinia speciosa. Phytochemistry. 1981;20(11):2503-06. https://doi.org/10.1016/0031-9422(81)830828
Abreu PM, Noronha RG. Volatile Constituents of the Rhizomes of Aframomum alboviolaceum (Ridley) K. Schum. from Guinea?Bissau. Flavour and Fragrance Journal. 1997;12(2):79-83. https://doi.org/10.1002/(SICI)1099-1026(199703)12:2<79::AID-FFJ617>-3.0.CO;2-7
Ahmed Hamdi OA, Syed Abdul Rahman SN, Awang K, Abdul Wahab N, Looi CY, Thomas NF et al. Cytotoxic constituents from the rhizomes of Curcuma zedoaria. The Scientific World Journal. 2014;2014. https://doi.org/10.1155/2014/321943
Yamauchi R. Vitamin E: mechanism of its antioxidant activity. Food Science and Technology International, Tokyo. 1997;3(4):301-19. https://doi.org/10.3136/fsti9596t9798.3.-301
Knekt P, Aromaa A, Maatela J, Aaran R-K, Nikkari T, Hakama M et al. Vitamin E and cancer prevention. The American Journal of Clinical Nutrition. 1991;53(1):283S-6S. https://doi.org/10.1093/ajcn/53.1.283S
Kline K, Yu W, Sanders BG. Vitamin E and breast cancer. The Journal of Nutrition. 2004;134(12):3458S-62S. https://doi.org/10.1093/jn/134.12.3458S
Kim YS, Li XF, Kang KH, Ryu B, Kim SK. Stigmasterol isolated from marine microalgae Navicula incerta induces apoptosis in human hepatoma HepG2 cells. BMB reports. 2014;47(8):433. https://doi.org/10.5483/BMBRep.2014.47.8.153
Islam MT, Ali ES, Uddin SJ, Shaw S, Islam MA, Ahmed MI, et al. Phytol: A review of biomedical activities. Food and Chemical Toxicology. 2018;121:82-94. https://doi.org/10.1016/j.fct.2018.08.032
Balamurugan R, Duraipandiyan V, Ignacimuthu S. Antidiabetic activity of ?-sitosterol isolated from Lippia nodiflora L. in streptozotocin induced diabetic rats. European Journal of Pharmacology. 2011;667(1-3):410-48. https://doi.org/10.1016/j.ejphar.2011.05.025
Sundarraj S, Thangam R, Sreevani V, Kaveri K, Gunasekaran P, Achiraman S et al. ?-Sitosterol from Acacia nilotica L. induces G2/M cell cycle arrest and apoptosis through c-Myc suppression in MCF-7 and A549 cells. Journal of Ethnopharmacology. 2012;141(3):803-39. https://doi.org/10.1016/j.jep.2012.03.014
Choochote W, Chaiyasit D, Kanjanapothi D, Rattanachanpichai E, Jitpakdi A, Tuetun B et al. Chemical composition and anti-mosquito potential of rhizome extract and volatile oil derived from Curcuma aromatica against Aedes aegypti (Diptera: Culicidae). Journal of Vector Ecology. 2005;30(2):302.
Grover M, Behl T, Sehgal A, Singh S, Sharma N, Virmani T et al. In vitro phytochemical screening, cytotoxicity studies of Curcuma longa extracts with isolation and characterisation of their isolated compounds. Molecules. 2021;26(24):7509. https://doi.org/-10.3390/molecules26247509
Mehra N, kumar Jain N. Comparative phytochemical screening of Curcuma angustifolia, Curcuma decipiens and Curcuma longa by using GC-MS. Journal of Pharmacognosy and Phytochemistry. 2019;8(2):1227-34.
Al-Salih DAAK, Aziz FM, Mshimesh BAR, Jehad MT. Antibacterial effects of vitamin E: In vitro study. Journal of Biotechnology Research Center. 2013;7(2):17-23. https://doi.org/10.24126/jobrc.2013.7.2.260
Mailafiya MM, Yusuf AJ, Abdullahi MI, Aleku GA, Ibrahim IA, Yahaya M et al. Antimicrobial activity of stigmasterol from the stem bark of Neocarya macrophylla. Journal of Medicinal Plants for Economic Development. 2018;2(1):1-5. https://doi.org/10.4102/-jomped.v2i1.38
Bindu BSC, Mishra DP, Narayan B. Inhibition of virulence of Staphylococcus aureus–a food borne pathogen–by squalene, a functional lipid. Journal of functional foods. 2015;18:224-34. https://doi.org/10.1016/j.jff.2015.07.008
Ukaegbu-Obi KM, Ifediora AC, Ifediora NH, Chukwu B. In vitro combine d antibacterial effect of Turmeric (Curcuma longa) and Ginger (Zingiber officinale) on some pathogenic organisms. Analele Universit??ii din Oradea, Fascicula Biologie. 2016;23(1):32-36.
Kim HJ, Lee JW, Kim YD. Antimicrobial activity and antioxidant effect of Curcuma longa, Curcuma aromatica and Curcuma zedoaria. Korean Journal of Food Preservation. 2011;18(2):219-25. https://doi.org/10.11002/kjfp.2011.18.2.219
Chandrasekaran K, Senthilkumar M. Synergic antibacterial effect of Curcuma aromatica Salisb. and Ocimum tenuiflorum Linn herbal extract combinations on treated cotton knitted fabrics against selective bacterial strains. Indian Journal of Fibre and Textile Research (IJFTR). 2019;44(3):344-51. https://doi.org/10.56042/ijftr.v44i3.21168
Downloads
Published
Versions
- 01-04-2023 (2)
- 07-03-2023 (1)
How to Cite
Issue
Section
License
Copyright (c) 2022 Hong Thien Van, Minh Dang Tran, Thi Kim Ngan Tran, Hanh Thi-Dieu Nguyen, Ngoc-An Nguyen, Nguyen Tuong An Huynh, Van Son Le, Quoc Hung Nguyen, Thanh Tho Le, Nga Nguyen Phi, Tan-Viet Pham
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright and Licence details of published articles
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
Open Access Policy
Plant Science Today is an open access journal. There is no registration required to read any article. All published articles are distributed under the terms of the Creative Commons Attribution License (CC Attribution 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited (https://creativecommons.org/licenses/by/4.0/). Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).