Chemical profiles and antibacterial activity of acetone extract of two Curcuma species from Vietnam

Authors

  • Hong Thien Van Institute of Biotechnology and Food technology, Industrial University of Ho Chi Minh City, 12 Nguyen Van Bao Street, Go Vap District, Ho Chi Minh City, Vietnam. https://orcid.org/0000-0003-0151-5068
  • Minh Dang Tran Institute of Biotechnology and Food technology, Industrial University of Ho Chi Minh City, 12 Nguyen Van Bao Street, Go Vap District, Ho Chi Minh City, Vietnam. https://orcid.org/0000-0002-1688-511X
  • Thi Kim Ngan Tran Institute of Biotechnology and Food technology, Industrial University of Ho Chi Minh City, 12 Nguyen Van Bao Street, Go Vap District, Ho Chi Minh City, Vietnam. https://orcid.org/0000-0002-1364-0053
  • Hanh Thi-Dieu Nguyen Institute of Biotechnology and Food technology, Industrial University of Ho Chi Minh City, 12 Nguyen Van Bao Street, Go Vap District, Ho Chi Minh City, Vietnam. https://orcid.org/0000-0002-3735-9127
  • Ngoc-An Nguyen Institute of Biotechnology and Food Technology, Industrial University of Ho Chi Minh City, No. 12 Nguyen Van Bao Street, Go Vap District, Ho Chi Minh City, Vietnam https://orcid.org/0000-0002-7574-2952
  • Nguyen Tuong An Huynh Institute of International and Postgraduate Education, Industrial University of Ho Chi Minh City, 12 Nguyen Van Bao Street, Go Vap District, Ho Chi Minh City, Vietnam https://orcid.org/0000-0003-0015-7158
  • Van Son Le Binh Chau-Phuoc Buu Nature Reserve, Bung Rieng Ward, Xuyen Moc District, Ba Ria-Vung Tau Province, Vietnam. https://orcid.org/0000-0003-0151-0646
  • Quoc Hung Nguyen Center of Analytical Services and Experimentation HCMC, Vietnam, 2 Nguyen Van Thu, Dakao Ward, District 1, Ho Chi Minh City, Vietnam. https://orcid.org/0000-0003-2668-6293
  • Thanh Tho Le Center of Analytical Services and Experimentation HCMC, Vietnam, 2 Nguyen Van Thu, Dakao Ward, District 1, Ho Chi Minh City, Vietnam. https://orcid.org/0000-0002-6303-3235
  • Nga Nguyen Phi Department of Ecology and Evolutionary Biology, University of Science, Vietnam National University HCMC, 227 Nguyen Van Cu Street, District 5, Ho Chi Minh City, Vietnam. https://orcid.org/0000-0001-7429-3641
  • Tan-Viet Pham Institute of Biotechnology and Food technology, Industrial University of Ho Chi Minh City, 12 Nguyen Van Bao Street, Go Vap District, Ho Chi Minh City, Vietnam. https://orcid.org/0000-0002-1061-1257

DOI:

https://doi.org/10.14719/pst.1993

Keywords:

Curcuma thorelii, Curcuma cotuana, GC/MS, Chemical composition, Antibacterial activity

Abstract

Curcuma thorelii Gagnep. and Curcuma cotuana Luu, Škorni?k. & H.?.Tr?n are the rare species only found in Southeast Asia. The present study was the first to explore the chemical compositions and antibacterial effects of the whole plant acetone extracts of these 2 species. Altogether 41 and 31 compounds have been identified in C. thorelii and C. cotuana extracts by gas chromatography/mass spectrometry. Accordingly, the C. thorelii extract contained (E)-labda-8(17),12-diene-15,16-dial (33.37%), vitamin E (12.33%), phytol (9.83%) as the major compounds while C. cotuana extract contained predominantly (E)-labda-8(17),12-diene-15,16-dial (14.58%), n-hexadecanoic acid (10.96%), 3,7,11,15-tetramethylhexadec-2-en-1-yl acetate (8.13%), ?-sitosterol (7.97%). In addition, results from disc diffusion assay have shown that C. thorelii acetone extract had inhibitory effects on 5 out of 10 pathogenic bacterial strains such as Bacillus cereus (ATCC 11778), Listeria monocytogenes (ATCC 19111), Staphylococcus aureus (ATCC 25923), S. aureus (ATCC 29213) and S. saprophyticus (BAA750) while C. cotuana acetone extract was found to be effective only against B. cereus. The obtained results showed that the acetone extracts of C. thorelii and C. cotuana possessed several valuable bioactive compounds as well as promising antibacterial activity, which place a good foundation for future pharmaceutical product development.

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Published

07-03-2023 — Updated on 01-04-2023

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How to Cite

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Van HT, Tran MD, Tran TKN, Nguyen HT-D, Nguyen N-A, Huynh NTA, Le VS, Nguyen QH, Le TT, Nguyen Phi N, Pham T-V. Chemical profiles and antibacterial activity of acetone extract of two Curcuma species from Vietnam. Plant Sci. Today [Internet]. 2023 Apr. 1 [cited 2024 Nov. 4];10(2):83-9. Available from: https://horizonepublishing.com/journals/index.php/PST/article/view/1993

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