Unveiling the pharmacological potential of guava (Psidium guajava L.): A review
DOI:
https://doi.org/10.14719/pst.5758Keywords:
bioactive compounds, biological effects, nutritional benefits, therapeutic propertiesAbstract
Guava, a tropical fruit renowned for its rich nutritional profile, has garnered increasing attention in the field of pharmacology due to its diverse bioactive compounds. This resilient plant flourishes in tropical and subtropical climates, making it well-suited to warm environments. Guavas are climacteric fruits, which means they continue to ripen after being harvested. They are renowned for their nutritional profile, rich in potassium, lycopene, manganese, iron, calcium, fiber and essential vitamins and minerals. The guava plant's fruit and leaves possess a range of edible and medicinal properties. Guava extracts are recognized for their health benefits, which include anticancer, antiobesity, antibacterial, antidiabetic and antihypertensive effects. The presence of phytochemicals in guava leaves, such as caffeic acid, flavonoids and hyperin, enhances their therapeutic potential, particularly in treating respiratory ailments like coughs and colds. Guava’s impressive health-promoting qualities have made it a valuable addition to traditional medicine practices. Its fruits are not only delicious but also serve as a natural remedy for various conditions, highlighting the plant's versatility. By incorporating guava into the diet, individuals can benefit from its wide-ranging health advantages, making it a worthwhile fruit to include in daily nutrition. Overall, guava stands out as a powerhouse of nutrients and therapeutic properties, contributing significantly to health and wellness.
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References
Pommer CV, Murakami KR. Breeding guava (Psidium guajava L.). In: Breeding plantation tree crops: Tropical Species. Springer, New York. 2009;3(2):83-120. https://link.springer.com/chapter/10.1007/978-0-387-71201-7_3
Pandhi S, Kumar A, Rai DC. Efficacy evaluation of extraction technologies for guava (Psidium guajava L.) leaves extract. Annals of Phytomedicine. 2022;11(1):413-18.
Narayanankutty A. Pharmacological potentials and nutritional values of tropical and subtropical fruits of India: Emphasis on their anticancer bioactive components. Recent Patents on Anti-Cancer Drug Discovery. 2022;17(2):124-35. https://www.ingentaconnect.com/content/ben/pra/2022/00000017/00000002/art00002
Rani R, David J. A review on utility of an astonishing fruit: Psidium guajava (guava). J Sci and Technol (JST). 2021;6(1):60-72. https://jst.org.in/index.php/pub/article/view/260
Upadhyay R, Dass JF, Chauhan AK, Yadav P, Singh M, Singh RB. Guava enriched functional foods: therapeutic potentials and technological challenges. The Role of Functional Food Security in Global Health. 2019;8(3):365-78. https://www.sciencedirect.com/science/article/pii/B9780128131480000219
Yadav A, Kumar N, Upadhyay A, Fawole OA, Mahawar MK, Jalgaonkar K, et al. Recent advances in novel packaging technologies for shelf-life extension of guava fruits for retaining health benefits for longer duration. Plants. 2022;11(4):547. https://www.mdpi.com/2223-7747/11/4/547
Tousif MI, Nazir M, Saleem M, Tauseef S, Shafiq N, Hassan L, et al. Psidium guajava L. An incalculable but underexplored food crop: Its phytochemistry, ethnopharmacology and industrial applications. Molecules. 2022;27(20):7016. https://www.mdpi.com/1420-3049/27/20/7016
Kanwal N, Randhawa MA, Iqbal Z. A review of production, losses and processing technologies of guava. Asian J Agri Food Sci. 2016 ;4(02):312-24. https://www.academia.edu/download/45000530/3522-12552-1-PB.pdf
Wong CK, Teh CY. Impact of biofertilizers on horticultural crops. Biofertilizers: Study and Impact. 2021;3(7):39-103. https://doi.org/10.1002/9781119724995.ch2
Garg S, Paliwal R. Green technologies for restoration of damaged ecosystem. Soil Health Restor Manage. 2020;6(2):357-80. https://link.springer.com/chapter/10.1007/978-981-13-8570-4_10
Dolkar D, Bakshi P, Wali VK, Bhushan B, Sharma A. Growth and yield attributes of commercial guava (Psidium guajava L.) cultivars under sub-tropical condition. Indian J Plant Physiol. 2014;19:79-82. https://link.springer.com/article/10.1007/s40502-014-0076-9
Singh D, Wesley CJ, Bahadur V. Effect of integrated nutrient management on meadow orcharding of guava for better growth, yield. J Adv Biol Biotechnol. 2024;27(7):1175-81. http://publish.journalgazett.co.in/id/eprint/2081/
Rana RA, Siddiqui MN, Skalicky M, Brestic M, Hossain A, Kayesh E, et al. Prospects of nanotechnology in improving the productivity and quality of horticultural crops. Horticulturae. 2021;7(10):332. https://www.mdpi.com/2311-7524/7/10/332
Yadav S, Pratap R, Yadav A, Yadav L, Chaudhary AK, Verma S, Tyagi A. A review on crop regulation in guava fruit. Int J Environ Climate Change. 2023;13(10):44-52.
Asrey R, Sharma S, Barman K, Prajapati U, Negi N, Meena NK. Biological and postharvest interventions to manage the ethylene in fruit: a review. Sustainable Food Technology. 2023. https://pubs.rsc.org/en/content/articlehtml/2023/fb/d3fb00037k
Kaur M. Effect of plant growth regulators on physiology, yield and quality of guava. Annals of Horticulture. 2020;13(2):131-45.
Parvez GM, Shakib U, Khokon M, Sanzia M. A short review on a nutritional fruit: guava. Open Access Toxicol Res. 2018;1:1-8. https://www.researchgate.net/330702066/5c543235a6fdccd6b5d93c14.pdf
Lakshmi EN, Kumar S, Sudhir DA, Jitendrabhai PS, Singh S, Jangir S. A review on nutritional and medicinal properties of guava (Psidium guajavaL.). Annals of Phytomedicine. 2022;11(2):240-49.
Ryu NH, Park KR, Kim SM, Yun HM, Nam D, Lee SG, et al. A hexane fraction of guava leaves (Psidium guajava L.) induces anticancer activity by suppressing AKT/mammalian target of rapamycin/ribosomal p70 S6 kinase in human prostate cancer cells. Journal of Medicinal Food. 2012;15(3):231-241. https://www.liebertpub.com/doi/abs/10.1089/jmf.2011.1701
Peng CC, Peng CH, Chen KC, Hsieh CL, Peng RY. The aqueous soluble polyphenolic fraction of Psidium guajava leaves exhibits potent anti-angiogenesis and anti-migration actions on DU145 cells. Evid-Based Comp Alter Med. 2011;3(1):219069. https://onlinelibrary.wiley.com/doi/abs/10.1093/ecam/neq005
Pelegrini PB, Murad AM, Silva LP, Dos Santos RC, Costa FT, Tagliari PD, et al. Identification of a novel storage glycine-rich peptide from guava (Psidium guajava) seeds with activity against gram-negative bacteria. Peptides.2008A;29(8):12719. https://www.sciencedirect.com/science/article/pii/S0196978108001319
Huang CS, Yin MC, Chiu LC. Antihyperglycemic and antioxidative potential of Psidium guajava fruit in streptozotocin-induced diabetic rats. Food and Chemical Toxicology. 2011 Sep 1;49(9):2189-95. https://doi.org/10.1016/j.fct.2011.05.032
Kafle A, Mohapatra SS, Reddy I, Chapagain M. A review on medicinal properties of Psidium guajava. J Med Plants Stud. 2018;6(4):44-57. https://www.plantsjournal.com/archives/2018/vol6issue4/PartA/6-4-11-994.pdf
Raja NR, Sundar K. Psidium guajava Linn confers gastro protective effects on rats. Europe Rev Med Pharmacol Sci. 2012;16(2):243-58. http://www.europeanreview.org/wp/wp-content/uploads/1099.pdf
Uduak EU, Timbuak JA, Musa SA, Ikyembe DT, Abdurrashid S, Hamman WO. Ulceroprotective effect of methanol extract of Psidium guajava leaves on ethanol induced gastric ulcer in adult wistar rats. Asian J Med Sci. 2012;4(2):75-78. https://www.academia.edu/download/71620216/20211006-13178
Okoli CO, Ezike AC, Akah PA, Udegbunam SO, Okoye TC, Mbanu TP, Ugwu E. Studies on wound healing and antiulcer activities of extract of aerial parts of Phyllanthus niruri L. (Euphorbiaceae). Amer J Pharmacol Toxicol. 2009;4(4):118-26. https://www.cabidigitallibrary.org/doi/full/10.5555/20103073702
Shaheena S, Chintagunta AD, Dirisala VR, Sampath KNS. Extraction of bioactive compounds from Psidium guajava and their application in dentistry. AMB Express. 2019;9:1-9. https://link.springer.com/article/10.1186/s13568-019-0935-x
Thakur R, Jain N, Pathak R, Sandhu SS. Practices in wound healing studies of plants. Evid-Based Comp Alter Med. 2011;7(5):1-17. https://pubmed.ncbi.nlm.nih.gov/21716711/
Diaz-de-Cerio E, Gómez-Caravaca AM, Verardo V, FernándezGutiérrez A, Segura-Carretero A. Determination of guava (Psidium guajava L.) leaf phenolic compounds using HPLC-DAD-QTOF-MS. Journal of Functional Foods. 2016;22:376-88. https://doi.org/10.1016/j.jff.2016.01.040
Dos Santos AF, Da Silva AS, Galli GM, Paglia EB, Dacoreggio MV, Kempka AP, et al. Addition of yellow strawberry guava leaf extract in the diet of laying hens had antimicrobial and antioxidant effect capable of improving egg quality. Biocatalysis and Agricultural Biotechnology. 2020;29:101788. https://doi.org/10.1016/j.bcab.2020.101788
Kumar M, Tomar M, Amarowicz R, Saurabh V, Nair MS, Maheshwari C, et al. Guava (Psidium guajava L.) leaves: Nutritional composition, phytochemical profile and health-promoting bioactivities. Foods. 2021;10(3):752.
Manikandan R, Anand AV, Muthumani GD. Phytochemical and in vitro anti-diabetic activity of methanolic extract of Psidium guajava leaves. Int J Curr Microbiol Appli Sci. 2013;2(2):15-19. https://www.academia.edu/download/36734051/Manikandan_etal.pdf
Wang B, Jiao S, Liu H, Hong J. Study on antioxidative activities of Psidium guajava Linn leaves extracts. Wei Sheng yan jiu Journal of Hygiene Research. 2007;36(3):298-300. https://europepmc.org/article/med/17712944
Abdelrahim SI, Almagboul AZ, Omer ME, Elegami A. Antimicrobial activity of Psidium guajava L. Fitoterapia. 2002;73(7-8):713-15. https://doi.org/10.1016/S0367-326X(02)00243-5
Gutierrez RM, Mitchell S, Solis RV. Psidium guajava: A review of its traditional uses, phytochemistry and pharmacology. Journal of Ethnopharmacology. 2008;117(1):1-27. https://doi.org/10.1016/j.jep.2008.01.025
Puntawong S, Okonogi S, Pringproa K. In vitro antibacterial activity of Psidium guajava Linn. leaf extracts against pathogenic bacteria in pigs. Chiang Mai Univ J Nat Sci. 2012;11(2):12734. https://www.thaiscience.info/Journals/Article/CMUJ/10887409
Chen KC, Peng CC, Chiu WT, Cheng YT, Huang GT, Hsieh CL, Peng RY. Action mechanism and signal pathways of Psidium guajava L. aqueous extract in killing prostate cancer LNCaP cells. Nutrition and Cancer. 2010;62(2):260-70. https://doi.org/10.1080/01635580903407130
Vinayagam R, Jayachandran M, Chung SS, Xu B. Guava leaf inhibits hepatic gluconeogenesis and increases glycogen synthesis via AMPK/ACC signaling pathways in streptozotocin-induced diabetic rats. Biomedicine and Pharmacotherapy. 2018;103:1012-17. https://www.sciencedirect.com/science/article/pii/S0753332217362303
Jaiarj P, Khoohaswan P, Wongkrajang Y, Peungvicha P, Suriyawong P, Saraya MS, Ruangsomboon O. Anticough and antimicrobial activities of Psidium guajava Linn. leaf extract. Journal of Ethnopharmacology. 1999;67(2):203-12. https://doi.org/10.1016/S0378-8741(99)00022-7
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