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Plant Science Today (PST)

Research Articles

Early Access

Isolation, characterization and bioactive properties of polysaccharides extracted from the peel of Cucumis melo Mill. (Gurvak variety)

DOI
https://doi.org/10.14719/pst.9461
Submitted
16 May 2025
Published
05-11-2025
Versions

Abstract

Melon peel is a by-product that contains significant amounts of bioactive substances. It has potential for developing functional foods. In this work, we studied the chemical composition of melon peel from the Gurvak variety, including various fractions of polysaccharides and their monosaccharides, free amino acids, water-soluble (WS) vitamins and flavonoids. The fractions of WS, acidic and basic polysaccharides were obtained with yields of 14.5 %, 4.60 % and 5.63 %, respectively. Their viscosity results were linked with the carboxyl group-related parameters and molecular masses. The dominant molar mass of free amino acids was attributed to nonessential amino acids, with glycine and glutamine being the most abundant ones. In the peel pulp, flavonoids and vitamins were determined in nanomolar and micromolar concentration, respectively. After oral administration at a dose of 5000 mg/kg, the WS polysaccharides showed no toxicity in mice. Furthermore, the fraction exhibited wound-healing properties that accelerated skin recovery in mice. The polysaccharides extracted from the melon peel of the local Gurvak variety may  be used as a wound-healing source. In terms of free amino acids, both the quantity and quality may not be appropriate for functional foods. A similar conclusion can be drawn made for quantities of flavonoids and vitamins. The results obtained can serve to expand knowledge and support further analysis in this discipline, which may lead to technological improvements.

References

  1. 1. Munger H, Robinson RW. Nomenclature of Cucumis melo. Cucurbit Genetics Cooperative. 1991;14(7):43–44.
  2. 2. Hakimov RA, Nzomov RA, Mavlyanova RF, Rustamov AS. Oʻzbekiston polizchiligi / Бахчеводство Узбекистана / Gourds of Uzbekistan. Rome: Food and Agriculture Organization of the United Nations (FAO); 2024.
  3. 3. Food and Agriculture Organization of the United Nations (FAO). Responsible Consumption and Production – Ensure Sustainable Consumption and Production Patterns. Rome: FAO; 2022.
  4. 4. Rolim PM, Seabra LMJ, de Macedo G. Melon by-products: Biopotential in human health and food processing. Food Reviews International. 2020;36, 15–38. https://doi.org/10.1080/87559129.2019.1613662
  5. 5. Lima SKR, Durazzo A, Lucarini M, de Oliveira JJA, da Silva RA, Arcanjo DDR. Valorization of fruit co-product flours for human nutrition: Challenges, applications and perspectives. Sustainability. 2023;15:13665. https://doi.org/10.3390/su151813665
  6. 6. Feizy J, Jahani M, Ahmadi S. Antioxidant activity and mineral content of watermelon peel. Journal of Food and Bioprocess Engineering. 2020;3, 35–40. https://doi.org/10.22059/jfabe.2020.75811
  7. 7. Molina OM, Domínguez-Avila JA, Pareek S, Santana TJM, Aguilar GAG, et al. Valorization of tropical fruit peel powders: Physico-chemical composition, techno-functional properties and in vitro antioxidant and antidiabetic activities. Emirates Journal of Food and Agriculture. 2023;35, 577–87 https://doi.org/10.9755/ejfa.2023.v35.i6.3105
  8. 8. Hussain A, Laaraj S, Tikent A, Elfazazi K, Adil M, Parveen S, et al. Physicochemical and phytochemical analysis of three melon fruit (canary melon, watermelon and muskmelon) peels and their valorization in biscuits development. Frontiers in Sustainable Food Systems. 2024;8:1444017. https://doi.org/10.3389/fsufs.2024.1444017
  9. 9. Gómez-García R, Campos DA, Oliveira A, Aguilar CN, Madureira AR, Pintado M. A chemical valorisation of melon peels towards functional food ingredients: Bioactives profile and antioxidant properties. Food Chemistry. 2021;335:127579. https://doi.org/10.1016/j.foodchem.2020.127579
  10. 10. Mallek-Ayadi S, Bahloul N, Kechaou N. Characterization, phenolic compounds and functional properties of Cucumis melo L. peels. Food Chemistry. 2017;221, 1691-97. https://doi.org/10.1016/j.foodchem.2016.10.117
  11. 11. Pan H, Li M, Liu T, Qi H. Multi-microscopy techniques combined with FT-IR spectroscopy reveals the histological and biochemical causes leading to fruit texture difference in oriental melon (Cucumis melo var. Makuwa Makino). Food Chemistry. 2023;402:134229. https://doi.org/10.1016/j.foodchem.2022.134229
  12. 12. Raji Z, Khodaiyan F, Rezaei K, Kiani H, Hosseini SS. Extraction optimization and physicochemical properties of pectin from melon peel. International Journal of Biological Macromolecules. 2017;98:709-716. https://doi.org/10.1016/j.ijbiomac.2017.01.146
  13. 13. Kumar S, Konwar J, Purkayastha MD, Kalita S, Mukherjee A, Dutta J. Current progress in valorization of food processing waste and by-products for pectin extraction. International Journal of Biological Macromolecules. 2023;239:124332. https://doi.org/10.1016/j.ijbiomac.2023.124332
  14. 14. Gómez-García R, Sousa SC, Ramos ÓL, Campos DA, Aguilar CN, Madureira AR, et al. Obtention and Characterization of Microcrystalline Cellulose from Industrial Melon Residues Following a Biorefinery Approach. Molecules. 2024;29:3285. https://doi.org/10.3390/molecules29143285
  15. 15. Silva MA, Gonçalves Albuquerque T, Espírito Santo L, Motta C, Almeida A, Azevedo R, et al. Exploring the Functional Features of Melon Peel Flour for Healthier Bakery Products. Foods. 2025;14:40. https://doi.org/10.3390/foods14010040
  16. 16. Silva MA, Albuquerque TG, Alves RT, Oliveira MBPP, Costa HS, Melon (Cucumis melo L.) by-products: Potential food ingredients for novel functional foods?. Trends in Food Science & Technology. 2020;98:181-189. https://doi.org/10.1016/j.tifs.2018.07.005
  17. 17. Tang W, Liu D, Yin JY, Nie SP. Consecutive and progressive purification of food‐derived natural polysaccharide: Based on material, extraction process and crude polysaccharide. Trends in Food Science & Technologies. 2020;99;76-87. https://doi.org/10.1016/j.tifs.2020.02.015
  18. 18. Liu Z., Pi F., Guo X., Yu S. Characterization of the structural and emulsifying properties of sugar beet pectins obtained by sequential extraction. Food Hydrocolloids. 2019;88:31-42. https://doi.org/10.1016/j.foodhyd.2018.09.036
  19. 19. Ai C, Guo X, Lin J, Zhang T, Meng H. Characterization of the properties of amphiphilic, alkaline soluble polysaccharides from sugar beet pulp. Food Hydrocolloids. 2019;94:199-209. https://doi.org/10.1016/j.foodhyd.2019.03.022
  20. 20. Brienzo M, Siqueira AF, Milagres AMF. Search for optimum conditions of sugarcane bagasse hemicellulose extraction. Biochemical Engineering Journal. 2009;46(2):199-204. https://doi.org/10.1016/j.bej.2009.05.012
  21. 21. Wang YX, Yin JY, Huang XJ, Nie SP. Structural characteristics and rheological properties of high viscous glucan from fruit body of Dictyophora rubrovolvata. Food Hydrocolloids. 2020;101:105514. https://doi.org/10.1016/j.foodhyd.2019.105514
  22. 22. Doublier J.L., Launay B. Rheology of galactomannan solutions: Comparative study of guar gum and locust bean gum. Journal of Texture Studies. 1981;12:151-172. https://doi.org/10.1111/j.1745-4603.1981.tb01229.x
  23. 23. OECD (2002), Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure, OECD Guidelines for the Testing of Chemicals, Section 4, OECD Publishing, Paris, https://doi.org/10.1787/9789264070943-en
  24. 24. Gómez-García R, Sánchez-Gutiérrez M, Freitas-Costa C, Vilas-Boas AA, Campos DA, Aguilar CN, et al. Prebiotic effect, bioactive compounds and antioxidant capacity of melon peel (Cucumis melo L. inodorus) flour subjected to in vitro gastrointestinal digestion and human faecal fermentation. Food Research International. 2022;154:111045. https://doi.org/10.1016/j.foodres.2022.111045

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