This study aims to assess the demographic structure and regeneration dynamics of Borassus akeassii Bayton, Ouédr. & Guinko in Southwestern Burkina Faso, with a focus on the influence of environmental conditions and human pressures. Using field data collected across ecologically contrasting sites, we quantified the population structure, density and regeneration patterns of this palm species. The study employed a variable-area sampling design, with a standardised number of plots established at each site to account for variability in environmental conditions and land-use practices. The results reveal marked variability in the demographic structure of B. akeassii populations in southwestern Burkina Faso, largely influenced by geomorphological and soil conditions. The species is predominantly found on well-drained soils and is frequently incorporated into local agroecosystems. It exhibits spatial variability in its demographic structure, reflecting differences in ecological conditions and resource use practices. Despite relatively stable adult densities across sites, the observed population structure follows a reverse-J distribution, indicating ongoing natural regeneration. However, high juvenile mortality rates suggest potential constraints on long-term population renewal. In addition, a slight male-biased sex ratio in more intensively exploited areas points to the influence of harvesting practices on population dynamics. Overall, the findings highlight the combined role of environmental and anthropogenic factors in shaping B. akeassii populations. They emphasise the need for context-specific and participatory management strategies to ensure the sustainable conservation of this multifunctional species.