One of the path-breaking innovations in agriculture in recent decades is genetic engineering. Although subject to many criticisms, it also has the potential to be a game-changer if used with caution. As agricultural professionals can play a crucial intermediary role in genetically modified (GM) crop adoption, this study examined the factors influencing their purchase intentions regarding GM food. Through an online survey, data were collected from 230 agricultural professionals in India, including scientists, research assistants, line department officers, private sector employees and students. The effects of perceived benefits and attitudes toward the purchase intentions regarding GM foods were tested using an integrated framework with theory of planned behaviour and the benefit-risk analysis. The analysis revealed a significant relationship between perceived benefits and attitudes on purchase intentions. The results indicate that enriching knowledge through education and awareness of GMs helps build trust, which ultimately influences purchase intentions. It was noted that behavioural responses are shaped through interconnected pathways rather than isolated effects. Strategies such as mass media communication, transparent labelling and awareness initiatives led by scientific communities and organisations may enhance positive attitudes toward GM foods. The findings offer insights to the government, policymakers and agencies working on GMs to identify an effective channel for promoting this technology in society.