The rapid growth of cities and the shift toward highly urbanized lifestyles have distanced humanity from its innate connection with nature. This disconnection has taken a toll on mental health, physical well-being and overall quality of life. Biophilic gardens emerge as a revolutionary approach to reconnect people with nature by weaving natural elements into the fabric of urban environments. Rooted in the biophilia hypothesis, it emphasizes the profound psychological and physiological benefits of integrating features like greenery, natural light and organic forms into built spaces. This review explores the evolution of biophilic gardens, distinguishing it from sustainable design while underscoring its unique focus on nurturing human-nature relationships. Practical strategies, from incorporating green walls and water features in buildings to creating biodiverse urban landscapes, are discussed alongside compelling real-world examples. Projects like Singapore’s Khoo Teck Puat Hospital and Milan’s Bosco Verticale demonstrate how Biophilic gardens can transform spaces into vibrant, health-promoting ecosystems, enhancing well-being, productivity and environmental resilience. While the benefits are undeniable, challenges such as costs, maintenance and scalability remain hurdles. Looking ahead, the integration of smart technologies, biomimicry and regenerative practices could unlock new possibilities. Biophilic gardens offers a hopeful vision for the future, where cities become havens of harmony between humans and nature, fostering healthier, more sustainable communities.