This study analyses long-term yield trends of major crops in Tamil Nadu from 1965-66 to 2023-24 using descriptive statistics, compound annual growth rate (CAGR), Analysis of Variance (ANOVA) and linear regression. The analysis revealed notable inter-crop yield inequalities, with maize and groundnut exhibiting the greatest productivity increase. Meanwhile, pulses and minor millets continued to underperform. ANOVA validated the existence of significant yield disparities between the crops, emphasising the need for differentiated policy interventions. The trends also revealed consistent increases in groundnut and paddy, though maize exhibited more volatile yields. The results suggest some crops need more concentrated efforts, while some need to be neglected to optimise productivity and climate-resilient approaches need to be implemented. This study, in addition to advanced seamless frameworks for yield assessments, also provided India and other developing countries with a planning model for evidence-based agricultural strategies.