Qualitative and quantitative phytochemicals of leaves, bark and roots of Antiaris toxicaria Lesch., a promising natural medicinal plant and source of pesticides

Authors

  • Tjatjuk Subiono Mulawarman University, Samarinda, Indonesia
  • Sadarudin Mulawarman University, Samarinda, Indonesia
  • Mochammad Anang Tavip Regional Research and Development Center (Balitbangda), Tenggarong, Indonesia

DOI:

https://doi.org/10.14719/pst.1896

Keywords:

Toxicology, natural insecticide, HPLC, phytochemicals, Antiaris toxicaria

Abstract

Antiaris toxicaria Lesch. of the Moraceae family is a tree that grows endemic to Indonesia and has a height of about 20-30 m. This study aimed to screen the phytochemical constituents of leaf, bark and its root. The plant materials were collected from the Samarinda Botanical Garden. Latex of this species in Indonesia is known as a source of blowpipe poison. In other countries Antiaris sp. plant parts (leaves, bark and seeds) are used in ethnobotany practice as raw material for traditional medicine. The leaves, bark and seeds of this plant are used in the treatment of syphilis, leprosy, cancer and used as laxatives for sore throats. Screening of the phytochemical constituents of the samples began by tracing the macromolecules of alkaloids, steroids, tannins, phenolic compounds, flavonoids and saponins with various tests. Alkaloids, saponins, tannins, phlobatnins, flavonoids and terpenoids were detected in the chemical analysis. High performance liquid chromatography diode array detection (HPLC-DAD) was conducted. HPLC screening of A. toxicaria extracts revealed the presence of galic acid, catechins, chlorogenic acid, caffeic acid, ellagic acid, epigallocatechin, routine, isoquercitrin, quercitrin, quercetin and kaempferol. The study revealed the array of secondary metabolites present in the plant that can be used in medicinal preparations and will be candidate species for developing a natural insecticide.

Downloads

Download data is not yet available.

References

Berhaut J. Flore Illustree du Senegal: Dicotyledones, Tome VI: Linacées à Nymphéacées. Dakar: Ministère du Développement Rural et de l?Hydraulique. 1979:402-05.

Berg CC, Hijman ME, Weerdenburg JC. Flore du Cameroun: Moracées. Paris: Muséum National d?Histoire Naturelle, Laboratoire de Phanérogamie. 1985:104-10.

Ahmad M, Lim CP, Akowuah GA, Ismail NN, Hashim MA, Hor SY et al. Safety assessment of standardised methanol extract of Cinnamomum burmannii. Phytomedicine. 2013; Sep 15;20(12):1124-30. https://doi.org/10.1016/j.phymed.2013.05.005

Okogun JI, Spiff AI, Ekong DE. Triterpenoids and betaines from the latex and bark of Antiaris africana. Phytochemistry. 1976. https://doi.org/10.1016/S0031-9422(00)94464-9

Subiono T. Ligan Activity of Antiaris toxicaria Lesch. and the role of toxicarioside in crude extract: In Silico, In Vitro and In Vivo Approaches.

Rahmadi A, Hanafi MH, Setianingrum D, Widyastuti AD, Susilawati R. Physical, microbial and pesticide contaminations on fresh vegetable and fruit marketed in Samarinda-Indonesia. InIOP Conference Series: Earth and Environmental Science 2020 Feb 1 (Vol. 443, No. 1, p. 012062). IOP Publishing. https://doi.org/10.1088/1755-1315/443/1/012062

Huang S, Wang L, Liu L, Fu Q, Zhu D. Nonchemical pest control in China rice: a review. Agronomy for Sustainable Development. 2014 Apr;34(2):275-91. https://doi.org/10.1007/s13593-013-0199-9

Moronkola DO, Oladosu IA. Chemical Compositions of Lonchocarpus cyanescens Benth.,(Fabaceae)—Case study of its volatile oils and two triterpenoids. American Journal of Plant Sciences. 2013; Jul 30;2013. https://doi.org/10.4236/ajps.2013.48199

Edeoga HO, Okwu DE, Mbaebie BO. Phytochemical constituents of some Nigerian medicinal plants. African Journal of Biotechnology. 2005; Aug 19;4(7):685-88. https://doi.org/10.5897/AJB2005.000-3127

Evans WC. Trease and Evans' pharmacognosy. Elsevier Health Sciences; 2009 May 27.

Harborne JB, Williams CA. Advances in flavonoid research since 1992. Phytochemistry. 2000; Nov 1;55(6):481-504. https://doi.org/10.1016/S0031-9422(00)00235-1

Wink M. Ecological roles of alkaloids. Modern alkaloids. 2008; Jan 8:3-52.

Xu T, Li D, Jiang D. Targeting cell signaling and apoptotic pathways by luteolin: cardioprotective role in rat cardiomyocytes following ischemia/reperfusion. Nutrients. 2012; Dec;4(12):2008-19. https://doi.org/10.3390/nu4122008

Wizen G, Gasith A. Color variability and body size of larvae of two Epomis species (Coleoptera, Carabidae) in Israel, with a key to the larval stages. ZooKeys. 2011; (119):37. https://doi.org/10.3897/zookeys.119.1451

Faithfull NT. Methods In Agricultural Chemical Analysis A Practical Handbook. Cabi; 2002. https://doi.org/10.1079/9780851996080.0000

Desai SD, Desai DG, Kaur H. Saponins and their biological activities. Pharma Times. 2009; Mar;41(3):13-16.

Pagare S, Bhatia M, Tripathi N, Pagare S, Bansal YK. Secondary metabolites of plants and their role: Overview. Current Trends in Biotechnology and Pharmacy. 2015;9(3):293-304. https://doi.org/10.5958/2249-0035.2015.00016.9

Polya G. Biochemical targets of plant bioactive compounds: a pharmacological reference guide to sites of action and biological effects. CRC press; 2003 May 15. https://doi.org/10.1201/9780203013717

Olaleye MT, Akinmoladun AC, Ogunboye AA, Akindahunsi AA. Antioxidant activity and hepatoprotective property of leaf extracts of Boerhaavia diffusa Linn. against acetaminophen-induced liver damage in rats. Food and Chemical Toxicology. 2010 Aug 1;48(8-9):2200-05. https://doi.org/10.1016/j.fct.2010.05.047

Sathishkumar T, Baskar R, Shanmugam S. Optimization of flavonoids extraction from the leaves of Tabernaemontana heyneana wall using L16 orthogonal design.

Dai J, Mumper RJ. Plant phenolics: extraction, analysis and their antioxidant and anticancer properties. Molecules. 2010; Oct;15(10):7313-52. https://doi.org/10.3390/molecules15107313

Decker EA. The role of phenolics, conjugated linoleic acid, carnosine and pyrroloquinoline quinone as nonessential dietary antioxidants. Nutrition Reviews. 1995; Mar 1;53(3):49-58. https://doi.org/10.1111/j.1753-4887.1995.tb01502.x

Published

06-11-2022 — Updated on 01-01-2023

Versions

How to Cite

1.
Subiono T, Sadarudin, Tavip MA. Qualitative and quantitative phytochemicals of leaves, bark and roots of Antiaris toxicaria Lesch., a promising natural medicinal plant and source of pesticides. Plant Sci. Today [Internet]. 2023 Jan. 1 [cited 2024 Nov. 4];10(1):5-10. Available from: https://horizonepublishing.com/journals/index.php/PST/article/view/1896

Issue

Section

Research communications

Similar Articles

You may also start an advanced similarity search for this article.