Bio synthesis, Characterization of ZnO Nanoparticles from Scoparia dulcis L. plant extract and its in-vitro Antioxidant, Acetylcholinesterase Activity

R Mini; V Prabhu; K Poonkodi; K Vimaladevi; M Anusuya; M Vasuki

doi:10.14719/pst.2003

Authors

R Mini PG Department of Chemistry, Nallamuthu Gounder Mahalingam College, Pollachi, Tamil Nadu, India - 642 001 https://orcid.org/0000-0003-3923-427X
V Prabhu PG Department of Chemistry, Nallamuthu Gounder Mahalingam College, Pollachi, Tamil Nadu, India - 642 001 https://orcid.org/0000-0001-5899-9820
K Poonkodi PG Department of Chemistry, Nallamuthu Gounder Mahalingam College, Pollachi, Tamil Nadu, India - 642 001 https://orcid.org/0000-0002-0777-4485
K Vimaladevi PG Department of Chemistry, Nallamuthu Gounder Mahalingam College, Pollachi, Tamil Nadu, India - 642 001 https://orcid.org/0000-0002-7160-670X
M Anusuya PG Department of Chemistry, Nallamuthu Gounder Mahalingam College, Pollachi, Tamil Nadu, India - 642 001 https://orcid.org/0000-0001-8521-9746
M Vasuki PG Department of Chemistry, Nallamuthu Gounder Mahalingam College, Pollachi, Tamil Nadu, India - 642 001 https://orcid.org/0000-0002-3214-7061

DOI:

https://doi.org/10.14719/pst.2003

Keywords:

Scoparia dulcis, SDE –ZnO Nps, SEM, TEM, XRD, EDAX, Acetylcholinesterase (AChE) Activity, DPPH, ABTS assay

Abstract

The current investigation is focused on the use of green synthesis methods for zinc oxide nanoparticles (ZnO NPs) from Scoparia dulcis L. extract (SDE). SDE-mediated ZnO NPs (SDE-ZnO-NPs) were made using a simple and eco-friendly method that required little reaction time and calcinations temperature. UV-Vis, FTIR, X-ray powder diffraction, SEM, TEM & EDAX were used into characterizes the skeletal and synthetic properties concerning biosynthesized ZnO nonmaterial. The UV–Visible spectroscopy absorption peak for SDE-ZnO-NPs was found to be at 380 nm, confirming the production of ZnO NPs. The FTIR spectrum also revealed bioactive functional groups as well as metal-oxygen groups. Synthesized ZnO NPs had a rod shape in 200 nm, according to TEM examination. The Zn and O in the produced ZnO NPs were approved by the EDAX analysis. The XRD results revealed that it had a crystal structure that was similar to SDE-ZnO-NPs. The dose-related Acetylcholinesterase inhibitory action of SDE-ZnO NPs was determined utilizing the Ellman’s test. AChE activity of the synthesized nanoparticles showed potential inhibitory activity with IC50 values of 75.34 µg/mL. The antioxidant activity was investigated the biosynthesized ZnO-NPs using DPPH, ABTS assay.

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