Physicochemical characterization of commercially available Dhanwantharam Mezhupakam - An Ayurvedic oil formulation

Mansee  Thakur; Amita  Kirar; Tejaswini   Tajne; kapil Singh Thakur; Mini Mol; Himanshu Gupta

doi:10.14719/pst.2885

Authors

Mansee Thakur Department of Medical Biotechnology, MGMCRL &MGMSBS, MGMIHS, Navi Mumbai, India https://orcid.org/0000-0003-4743-1476
Amita Kirar Department of Medical Biotechnology, MGMCRL &MGMSBS, MGMIHS, Navi Mumbai, India https://orcid.org/0009-0006-7747-6295
Tejaswini Tajne Department of Medical Biotechnology, MGMCRL &MGMSBS, MGMIHS, Navi Mumbai, India https://orcid.org/0009-0006-9411-0447
kapil Singh Thakur Nuvox Healthcare Pvt, Ltd, Navi Mumbai, India https://orcid.org/0000-0001-5319-1216
Mini Mol Department of Clinical Embryology, MGMCRL &MGMSBS, MGMIHS, Navi Mumbai, India https://orcid.org/0000-0002-7239-0226
Himanshu Gupta Department of Medical Biotechnology, MGMCRL &MGMSBS, MGMIHS, Navi Mumbai, India https://orcid.org/0000-0003-2354-9314

DOI:

https://doi.org/10.14719/pst.2885

Keywords:

Chromatogram, Densitometry, Dhanwantharam mezhupakam, Heavy metal, HPTLC, Phytoconstituents

Abstract

As a neuroprotective and nervine tonic, Dhanwantharam Mezhupakam (DM) is a medicated polyherbal oil formulation made using an Ayurvedic method. It is made by steeping herbs in significant water while simmering Taliam oil for a long time with a paste-like herb mixture. The purpose of the current study was to establish its standard criteria in accordance with the monograph to preserve the product's safety, consistency and quality manufacturing while also determining its heavy metal concentration. Organoleptic assessment, physicochemical evaluation, phytochemical evaluation, chromatographic analysis for active ingredients and heavy metal analysis are some of the formulation-related criteria that are assessed. According to pharmacopeia standards, every metric was examined. According to the study's findings, the formulation was well-standardized in terms of its physical consistency, chemical profile, phytoconstituents and antibacterial properties. Additionally, it was discovered that the sample's heavy metal contents were within WHO and API-acceptable standards.

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