Microscopical, phytochemical, and LC/MS analysis of Ginkgo biloba leaves

Rasha  Eldalawy; Noor  Mohsen Nasser; Asmaa Mahdi Hussein

doi:10.14719/pst.3097

Authors

Rasha Eldalawy College of Pharmacy, Al-Turath University, Baghdad, Iraq https://orcid.org/0000-0002-1338-9823
Noor Mohsen Nasser Pharmacognosy and Medicinal Plant Department, College of Pharmacy/ Mustansiriyah University, Baghdad, Iraq https://orcid.org/0000-0002-3215-1749
Asmaa Mahdi Hussein College of Pharmacy, Al-Turath University, Baghdad, Iraq https://orcid.org/0009-0006-3333-4893

DOI:

https://doi.org/10.14719/pst.3097

Keywords:

Ginkgo bioloba, LC/MS, Metabolites, Qualitative analysis

Abstract

Every medicinal practitioner knows Ginkgo as the plant source of an extract that is good for memory improvement. Ginkgo biloba extract is classified as one of the medicines in the treatment of dementia and social exclusion brought by vascular or neurodegenerative disorders. In such disorders, the extract was reported to be successful in improving symptoms such as depression, attention, memory disturbances, vertigo, tinnitus, and anxiety. The aerial part of Ginkgo bioloba was obtained from China, Utilizing fresh leaves allows for a microscopic inspection, the concentrated extracts by soxhlet were screened by standard methods for the qualitative investigation of secondary metabolites present in the plant, and a small quantity of extract was analyzed by LC/MS instrument. Microscopical examination shows diacytic stomata, helical vessels, fiber, and unicellular unbranched trichomes. Qualitative analysis is positive for tannin, glycoside, flavonoid, terpene, and phenolic compounds detected while saponin, coumarin, and alkaloid gave a negative result. While LC/MS shows important compounds that have important biological activities such as phenolic acids, flavonoids, and flavonoid glycosides which are reported for their different pharmacological activity, the Ginkgo plant is a promising drug that can help in the treatment of different diseases and required further studies.

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