Anti-acne activity of Garcinia mangostana L.: A review
DOI:
https://doi.org/10.14719/pst.2014.1.3.39Keywords:
Garcinia mangostana, mangosteen, acneAbstract
Garcinia mangostana L. or mangosteen of the Clusiaceae has traditionally been employed as medicinal drugs for decades. A plethora of compounds are responsible for a wide range of medicinal properties and biological activities. The ethanol extract of the mangosteen rind has been found to be anti-inflammatory, antioxidant and anti-acne-causing bacteria. Many research studies have confirmed its potency, with the ethanol extract of the rind being able to inhibit pro-inflammatory cytokines (TNF-?) at relatively low concentration. DPPH assay also revealed its potent radical scavenging activity. The compound responsible for the antibacterial activity, a-mangostin, was especially potent and one of the compounds responsible for the anti-bacterial activity.
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Chomnawang, M. T., Surassmo, S., Nukoolkarn, V. S., & Gritsanapan, W. (2005). Antimicrobial effects of Thai medicinal plants against acne-inducing bacteria. Journal of Ethnopharmacology, 101(1-3), 330-333. PMid:16009519. http://dx.doi.org/10.1016/j.jep.2005.04.038
Chomnawang, M. T., Surassmo, S., Nukoolkarn, V. S., & Gritsanapan, W. (2007). Effect of Garcinia mangostana on inflammation caused by Propionibacterium acnes. Fitoterapia, 78(6), 401-408. http://dx.doi.org/10.1016/j.fitote.2007.02.019 PMid:17644272
Farnworth, R. N., & Bunyapraphatsara, N. (1992). Garcinia mangostana Linn. in Thai medicinal plants. Prachachon Bangkok.
Jung, H. A., Su, B. N., Keller, W. J., Mehta, R. G., & Kinghorn, A. D. (2006). Antioxidant xanthones from the pericarp of Garcinia mangostana (Mangosteen). Journal of Agriculture and Food Chemistry, 54(6), 2077-2082. http://dx.doi.org/10.1021/jf052649z PMid:16536578
Khumsupan, P., & Gritsanapan, W. (2013). Selected Thai medicinal plant for the treatment of acne: Garcinia mangostana Linn. In M. L. Elsaie (Ed.), Acne: Etiology, Treatment options and Social Effects (pp. 51-60). New York: Nova Science Publishers, Inc.
Obolskiy, D., Pischel, I., Siriwatanametanon, N., & Heinrich, M. (2009). Garcinia mangostana L.: a phytochemical and pharmacological review. Phytotherapy Research, 23(8), 1047-1065. http://dx.doi.org/10.1002/ptr.2730 PMid:19172667
Peres, V., Nagem, T. J., & de Oliveira, F. F. (2000). Tetraoxygenated naturally occurring xanthones. Phytochemistry, 55(7), 683-710. http://dx.doi.org/10.1016/S0031-9422(00)00303-4
Pothitirat, W., Chomnawang, M. T., & Gritsanapan, W. (2008). Anti-acne inducing bacteria activity and alpha-mangostin content of Garcinia mangostana fruit rind extracts from different provenience. Songklanakarin Journal of Science and Technology, 31(1), 41-47.
Pothitirat, W., Chomnawang, M. T., Supabphol, R., & Gritsanapan, W. (2009). Comparison of bioactive compounds content, free radical scavenging and anti-acne inducing bacteria activities of extracts from the mangosteen fruit rind at two stages of maturity. Fitoterapia, 80(7), 442-447. http://dx.doi.org/10.1016/j.fitote.2009.06.005 PMid:19524646
Pothitirat, W., Chomnawang, M. T., Supabphol, R., & Gritsanapan, W. (2010). Free radical scavenging and anti-acne activities of mangosteen fruit rind extracts prepared by different extraction methods. Pharmaceutical Biology, 48(2), 182-186. http://dx.doi.org/10.3109/13880200903062671 PMid:20645837
Pothitirat, W., Pithayanukul, P., Chomnawang, M. T., Supabphol, R., & Gritsanapan, W. (2009). Biological and chemical stability of mangosteen fruit rind extract. Functional Plant Science and Biotechnology, 3(1), 16-18.
Saralamp, P., Chuakul, W., Temsiiririkkul, R., & Clayton, T. (1996). Medicinal plants in Thailand. Bangkok. Thailand: Amarin printing and publishing public Co., Ltd.
Somsri, S., & Manassakorn, C. (2006). Amazing Thai Mangosteen (N. Chomchalow Ed.). Bangkok, Thailand: Horticultural Research Institute (HRI) - Department of Agriculture (DOA).
United States Department of Agriculture (2014). Garcinia mangostana L. Retrieved from http://plants.usda.gov/core/profile?symbol=GAMA10
Vieira, L. M., & Kijjoa, A. (2005). Naturally-occurring xanthones: recent developments. Current Medicinal Chemistry, 12(21), 2413-2446 http://dx.doi.org/10.2174/092986705774370682 PMid:16250871.
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