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Mini Reviews

Vol. 1 No. 3 (2014)

Anti-acne activity of Garcinia mangostana L.: A review

DOI
https://doi.org/10.14719/pst.2014.1.3.39
Submitted
29 April 2014
Published
14-08-2014

Abstract

Garcinia mangostana L. or mangosteen of the Clusiaceae has traditionally been employed as medicinal drugs for decades. A plethora of compounds are responsible for a wide range of medicinal properties and biological activities. The ethanol extract of the mangosteen rind has been found to be anti-inflammatory, antioxidant and anti-acne-causing bacteria. Many research studies have confirmed its potency, with the ethanol extract of the rind being able to inhibit pro-inflammatory cytokines (TNF-?) at relatively low concentration. DPPH assay also revealed its potent radical scavenging activity. The compound responsible for the antibacterial activity, a-mangostin, was especially potent and one of the compounds responsible for the anti-bacterial activity.

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