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Plant Science Today (PST)

Research Articles

Vol. 11 No. sp4 (2024): Recent Advances in Agriculture by Young Minds - I

Evaluation of anti - diabetic activity of palmyrah (palm jaggery and palm honey) (Borassus flabellifer L.) against streptozotocin - nicotinamide induced diabetic wistar rats

DOI
https://doi.org/10.14719/pst.5936
Submitted
18 October 2024
Published
28-12-2024 — Updated on 17-08-2025
Versions

Abstract

Value-added products derived from palmyrah (Borassus flabellifer L.), such as palm jaggery and palm honey, serve as alternative source of table sugar with a low glycemic index. During 2022-23, an experiment was to evaluate their anti-diabetic activity. The efficacy of palm jaggery and palm honey was assessed in diabetic rats at a dose of 200 mg/kg and their effects were compared to those of oral glimepiride in a 28-days randomized control study. Biochemical estimations and histopathological analyses revealed that palm jaggery and palm honey possess anti
-diabetic, antioxidant, anti-hyperglycemic and insulinogenic properties. These palmyrah products significantly enhanced insulin secretion by pancreatic β-cells, leading to a marked reduction in blood glucose levels, serum uric acid, creatinine and lipid peroxidise activity. Furthermore, the restoration of normal metabolic pathways reduced oxidative stress-induced mechanisms in diabetic rats treated with palmyrah jaggery and honey. Hence, palm products could be used as an adjuvant in the treatment of diabetes mellitus.

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