In Vitro Antiacne and Antidandruff activity of extracted stigmasterol from seed waste of safflower (Carthamus tinctorius L.)
DOI:
https://doi.org/10.14719/pst.2019.6.sp1.670Keywords:
Anti-acne, Anti-dandruff activity, stigmasterolAbstract
The present study deals with extraction of saponins and their characterization from the seed wastes of safflower. The presence of stigmasterol in the extracted safflower seed waste (S.W.S) was confirmed by Thin Layer Chromatography (TLC), followed by Fourier-Transform Infrared Spectroscopy (FTIR) and High Performance Liquid Chromatography (HPLC) on the basis of its peak compared with stigmasterol standard. FTIR showed the identical functional groups of butanolic extract of SSW with standard while TLC and HPLC showed their notable peak and retention time with the same. Further in-vitro antiacne and antidandruff microbial activity of extracted stigmasterol was confirmed by disc diffusion method. This preliminary study has exhibited anti-acne and anti dandruff potential of Safflower seed waste extract, in future which could be used in therapies and cosmetic applications.
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