Research Articles
Vol. 7 No. 3 (2020)
Fluorescence and FTIR markers for different taxa of Gymnema drug complex from Maharashtra
Department of Botany, Hon. Balasaheb Jadhav College, Ale, Pune, Maharashtra, 412 411, India
Department of Botany, Annasaheb Waghire College, Otur, Pune, Maharashtra, 412 409, India
Abstract
Gymnema sylvestre known as Madhunashini / Gudmar and being commercially traded as a remedy of diabetes. The other taxa of this genus are also used as alternative drugs. The drug standards are available for the former species but not for the alternative taxa. In the present study, four taxa of Gudmar complex are evaluated to develop drug identification markers through fluorescence study and FTIR analysis. These markers are successful in distinguishing individual drug samples. The study will help to find out the purity of the samples and also for verification of drugs.
References
1. Aravind K, Pradeepa R, Deepa R. Diabetes and coronary artery disease. Ind J Med Res. 2002;116:163-76
2. IDF. International Diabetes Federation [Internet]. IDF online; 2019 December 30. Available from: www.diabetes.co.uk/diabetes-prevalence.html
3. Karthikeyan S, Sanjappa M, Moorthy S. Flowering plants of India: Dicotyledons (Acanthaceae - Avicenniaceae). pp. 170-71. Kolkata: Botanical Survey of India; 2009
4. Chattopadhyay RR. Possible mechanism of antihyperglycemic effect of Gymnema sylvestre leaf extract. Gene Pharm. 1998;31:495-96. https://doi.org/10.1016/S0306-3623(97)00450-3
5. Rana TS, Sing KK, Rao RR. Some interesting reports on indigenous herbal remedies for Diabetes mellitus from India. In: Fourth International Congress on Ethnobiology; NBRI, Lucknow; pp. 47.1994
6. Persaud SJ, Raman Al-Majed H, Jones PM. Gymnema sylvestre stimulates insulin release in vitro by increased membrane permeability. J of Endocri. 1999;163(2):207-12. https://doi.org/10.1677/joe.0.1630207
7. Rahangdale SS. Development of Pharmacognostic standards for Gudmar complex from Maharashtra. [project report]. Savitribai Phule, Pune University, Pune; pp. 105.2019
8. Rahangdale SS, Rahangdale SR. Digitized inventory of medicinal plant resources of Maharashtra. [project report]. Agharkar Research Institute, Pune; pp. 164.2013
9. Infodrive India. Gymnema export data 2015 [Internet]. Online; 2019 April 16. Available from: www.infodiveindia,com/india.export.data.gymnema-export-data.aspx
10. Johanns ES, Vander Kolk, Van Gemert, HM Sijben AE, Peters PW, De Vries I. An enemic of epileptic seizures after consumption of herbal tea. Netherland Tijdscrift Geneeskunde 2002;146(17):813-16
11. Phua DH, Cham G, Seow E. Two instances of Chinese herbal medicine poisoning in Singapore. Singapore Med J. 2008;49(5):131-33
12. Gupta MK. Pharmacognostical evaluation of Grewia asiatica. Internat. J Plant Sci. 2006;1(2):249-51
13. Cooke T. The Flora of the Presidency of Bombay. London, Vol. II. (BSI Calcutta, Vol. I-III. Reprint 1958); pp. 207-45.1903. https://doi.org/10.5962/bhl.title.10884
14. Hooker JD. Flora of British India. Vol. IV; pp.1-78. (London): Oxford; 1885
15. Jagtap AP, Singh NP. Asclepiadaceae & Periplocaceae, Fascicles of Flora of India 24, pp.332. Calcutta: Botanical Survey of India; 1999
16. Singh NP, Lakshminarasimhan P, Karthikeyan S, Prasanna PV, editors. Flora of Maharashtra State, Dicotyledons Vol II. pp. 336-64. Calcutta: Botanical Survey of India; 2001
17. POWO. Plants of the world online. [Internet]. 2020 May 12. Available from: http://www.plantsoftheworldonline.org/taxon
18. Silverstein RM, Webster FX. Spectrometric identification of organic compounds. 6th ed. pp. 71-79. New York: John Wiley & Sons, Ic; 1996
19. Merck. IR spectrum table and chart. [Internet] Sigmaaldrich online; 2020 May 13. Available from http://www,sigmaaldrich.com/technical-documents/articles/biology/ir-spectrum-table.html
Downloads
Download data is not yet available.
