Efficient removal of pollutants from sewage is essential for maintaining the sustainability of the ecosystem, which means that effective biological methods must be explored. Compared to traditional physical and chemical methods, bioremediation is an attractive alternative method because of its low-cost, maintains ecological balance and helps rebuild the polluted environment. In particular, the sustainable bioremediation technology based on sulphate-reducing bacteria (SRB) is considered to be one of the best treatment schemes to alleviate environmental pollution. The present paper provides a brief summary of the approach used to remove pollutants using sulphate-reducing bacteria, an obligate anaerobic bacterium. SRB are recognized for their capacity to convert sulphate into hydrogen sulfide, which facilitates the precipitation of heavy metals, degradation of organic pollutants and forms a large number of metal sulfides. The analysis delves into the biological processes utilized by SRB, the ideal conditions for their effectiveness and the potential advantages and obstacles associated with integrating SRB into wastewater treatment facilities. Additionally, it confronts challenges such as odor control, hydrogen sulfide mitigation and microbial survival. By examining of current studies and technological progress, this analysis underscores the potential of SRB as a sustainable and effective remedy for enhancing wastewater treatment and mitigating environmental contamination.