A field experiment was conducted to assess the effects of plant growth regulators on the growth and yield of apical cuttings of potato (Solanum tuberosum L.). The study comprised thirteen treatments, including indole-3-acetic acid (IAA), indole-3-butyric acid (IBA) and 1-naphthaleneacetic acid (NAA) applied at 500, 750, 1000 and 1500 ppm, along with a control. Treatments were arranged in a Completely Randomized Design (CRD) with three replications. The experiment was carried out from March to July 2024 at the Instructional cum Experimental Farm, Department of Horticulture, SAS, Medziphema Campus, Nagaland University. Growth and yield parameters were recorded and analysed statistically using Analysis of Variance (ANOVA). Treatment T8 (IBA 1500 ppm) exhibited superior performance, producing the highest root parameters, including the number of primary roots (12.89), secondary roots (25.67), fresh root weight (0.018 g), dry root weight (0.014 g) and longest root length (7.97 cm). It also recorded the highest shoot growth, with shoot length (16.43 cm), diameter (7.00 mm), fresh weight (0.623 g) and dry weight (0.060 g). T8 showed the highest survival percentage (89.5 %), leaf area (1.78 cm²) and tuber yield per plant (110.30 g). However, T7 (IBA 1000 ppm) produced the highest number of mini tubers (8.78). The control (T13) recorded the lowest values for all traits. The study highlights IBA at 1500 ppm as optimal for growth and yield, while IBA at 1000 ppm is best for mini tuber production, aiding in enhanced potato productivity.