Phytochemical Contents and Antioxidant Activity of Medicinal Plants from the Rubiaceae Family in Thailand

Authors

  • Rungcharn Suksungworn Phyto-Chemodiversity and Ecology Research Unit, Department of Botany, Faculty of Science, Kasetsart University, Bangkean, Bangkok 109 00, Thailand http://orcid.org/0000-0001-6122-2019
  • Sutsawat Duangsrisai Phyto-Chemodiversity and Ecology Research Unit, Department of Botany, Faculty of Science, Kasetsart University, Bangkean, Bangkok 109 00, Thailand http://orcid.org/0000-0001-8251-2023

DOI:

https://doi.org/10.14719/pst.2021.8.1.882

Keywords:

Anti-radical, Traditional medicine, Herbal medicine, Nature products

Abstract

Several plants of the Rubiaceae family possess potential pharmacological properties, such as antioxidant activity, for subsequent drug development. We investigated the methanolic extracts from the bark and wood of five Rubiaceae species for phenolic and flavonoid contents and antioxidant activity. Regarding the phytochemical contents and antioxidant activity, Mitragyna diversifolia wood (437.57 ± 9.90 mg GAE g-1) and Haldina cordifolia wood (30.11 ± 0.20 mg QE g-1) displayed the highest total phenolic content (TPC) and total flavonoid content (TFC) respectively. Morinda coreia bark followed the highest antioxidant activities (IC50 = 360.58 ± 19.28 µg ml-1) in the 2,2-diphenyl-1-picrylhydrazyl radical scavenging activity (DPPH), Catunaregam tomentosa bark (IC50 = 13.96 ± 5.32 µg ml-1) in the nitric oxide radical scavenging activity (NO), M. coreia wood (IC50 = 918.27 ± 0.16 µg ml-1) in the superoxide radical scavenging activity (SO) and M. coreia wood (IC50 = 236.65 ± 1.66 µg ml-1) in ferric reducing antioxidant power activity (FRAP). The TPC and TFC displayed strong correlations with DPPH in M. diversifolia wood and with FRAP in M. diversifolia bark and wood. We found high correlation between TFC and FRAP in all plant extracts except C. tomentosa wood, while no relation was detected between TFC and NO in all plant extracts. Comparing Rubiaceae species, the highest antioxidant potential were showed in C. tomentosa bark. Overall, it is worth mentioning that the Rubiaceae species exhibit potential as a promising source of natural antioxidants.

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Author Biography

Sutsawat Duangsrisai, Phyto-Chemodiversity and Ecology Research Unit, Department of Botany, Faculty of Science, Kasetsart University, Bangkean, Bangkok 109 00, Thailand

Currently work as Assistant Professor.

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Published

01-01-2021

How to Cite

1.
Suksungworn R, Duangsrisai S. Phytochemical Contents and Antioxidant Activity of Medicinal Plants from the Rubiaceae Family in Thailand. Plant Sci. Today [Internet]. 2021 Jan. 1 [cited 2024 Nov. 4];8(1):24-31. Available from: https://horizonepublishing.com/journals/index.php/PST/article/view/882

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