Therapeutic herbs are recognized as valuable sources of bioactives that are utilized in pharmaceutical research. Pterocarpus dalbergioides Roxb. ex DC., commonly called as Andaman padauk or narra, is a medicinal tree endemic to the Andaman Islands, renowned for its therapeutic properties against various health conditions. In this study, phytochemical constituents were quantitatively analysed through Gas Chromatography- Mass Spectrometry (GC-MS) and antibacterial activity was evaluated. The GC-MS analysis indicated a presence of about 100 metabolities with major metabolites including bis(2-ethylhexyl) phthalate, alpha-methyl mannofuranoside, stigmasterol and dotriacontane. The antibacterial assay revealed inhibition zones ranging from 10-13mm and 8-11mm against Staphylococcus aureus, Escherichia coli respectively, with the bark extract of P. dalbergioides while the leaf extract showed inhibition zones of 8-9mm. This pioneering research on the endemic species provides valuable information for further pharmacological research.