Phytochemical analysis, antioxidant and anti-inflammatory activity of leaves and bark of Ceropegia rollae Hemadri

Authors

DOI:

https://doi.org/10.14719/pst.2021.8.3.906

Keywords:

Ceropegia rollae, anti-inflammatory, antioxidant activity, DPPH, FRAP

Abstract

The purpose of the present study is to evaluate in vitro antioxidant activity and anti-inflammatory activity of methanolic extract of the leaves and the bark of the plant Ceropegia rollae Hemadri. The antioxidant activity of the both leaves and bark extract was studied using FRAP and DPPH method. The in vitro anti-inflammatory activity and phytochemical characterization were carried using known protocols. The various phytochemical components such as total phenolics and flavonoids were determined. The plant Ceropegia rollae also contains tannis and ascorbic acid. This is related to the antioxidant activity of the plant Ceropegia rollae extract. The leaves shows good antioxidant and anti-inflammatory activity as compared to the bark. These can be used as natural antioxidant and anti-inflammatory agents.

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References

Mirgane NA, Shivankar VS, Kotwal SB et al. Waste pericarp of Ananas comosus in green synthesis zinc oxide nanoparticles and their application in waste water treatment. Materials Today: Proceedings. 2020 July 9. https://doi.org/10.1016/j.matpr.2020.06.045

Mirgane NA, Shivankar VS, Kotwal SB et al., Degradation of dyes using biologically synthesized zinc oxide nanoparticles. Materials Today: Proceedings. 2020 July 9. https://doi.org/10.1016/j.matpr.2020.06.037

Patil DD, Mhaske DK, Wadhawa. Antidiabetic activity of bark and root of Caesalpinia bonduc. IJPSR. 2011 Oct 01;2(10):2750-52.

Shivankar VS, Wadhawa GC. et al. Phytochemical analysis of the methanol extract from leaves of Hemidesmus indicus. European Journal of Biomedical and Pharmaceutical Sciences. 2016;3(12):539-43.

Wadhawa GC et al. Phytochemical analysis of the methanol extract from leaves of Paullinia pinnata. World journal of pharmacy and Pharmaceutical Sciences. 2016, Dec.;5(12):1673-83.

Gaikwad YA, Shivankar VS, Wadhawa GC, et al. Antioxidant effect of the root and leaves of solanum melongena Linn. World journal of Pharmacy and Pharmaceutical Sciences. 2016, Dec.; 5(12): 1767-72.

Wadhawa GC et al. Phytochemical Analysis of the Methanol extract from leaves of Cassia fistula L. Journal of Chemical and Pharmaceutical Research, 2016;8(12):243-47.

Dubey S, Ojha K, Chandrakar jagriti, Dehariya R, Vinodia S, Singh A, Dixit AK. Assessment of total phenolic content and antioxidant potentiality of selected Indian folk medicinal plants by spectrophotometric method. Plant Sci. Today. 2020;7(3):383-90. https://doi.org/10.14719/pst.2020.7.3.765

Irem AB, Ahmet CG, Hasan K, Erdem Y. Evaluation of the in vitro anti-inflammatory activity of Nerium oleander L. flower extracts and activity-guided isolation of the active constituents,” Records of Natural Products. 2018;12(2):128–41.

Harborne JB. Phytochemical Methods Chapman and Hall, London; 1973.

Schulz H, Baranska M. Identification and quantification of valuable plant Ceropegia rollae substances by IR and Raman spectroscopy. Vibrational Spectroscopy. 2007;43:13-25. https://doi.org/10.1016/j.vibspec.2006.06.001

Binet ML, Commereuc S, Chalchat JC, Lacoste J. Oxidation of polyterpenes: a comparison of poly ?, and poly ?, pinenes behaviours: Part I photo-oxidation. Journal of Photochemistry and Photobiology A: Chemistry. 1999;125:45-53. https://doi.org/10.1016/S1010-6030(98)00412-2

Talaty N, Takáts Z, Cooks RG. Rapid in situ detection of alkaloids in plant Ceropegia rollae tissue under ambient conditions using desorption electrospray ionization. Analyst. 2005;130:1624-33. https://doi.org/10.1039/B511161G

Tsuchiya H, Hayashi H, Sato M, Shimizu H, Linuma M. Quantitative analysis of all types of ??carboline alkaloids in medicinal plants and dried edible plants by high performance liquid chromatography with selective fluorometric detection. Photochemical analysis. 1999;10:247-53.

Liu L, Zhang Y, Tang, S. An efficient system to detect protein ubiquitination by agroinfiltration in Nicotiana benthamiana. The plant journal. 2010;61:893-903. https://doi.org/10.1111/j.1365-313X.2009.04109.x

Khan AM, Rizwana, Qureshi RA, Ullah F et al. Phytochemical analysis of selected medicinal plants of Margalla Hills and surroundings. Journal of Medicinal Plants Research. 2011;5 6017-23.

Khorasani AE, Mat RT, Mohajer S, Banisalam B. Antioxidant activity and total phenolic and flavonoid content of various solvent extracts from in vivo and in vitro grown Trifolium pratense L. (Red clover). Biomed Res Int. 2015;2015:1-11.

Ansari MY. Asclepiadaceae: genus- Ceropegia. Fascicles of Flora of India.1984;16:1-34.

Chatterjee, S. 1995. Global ‘hot spots’ of biodiversity. Curr. Sci. 68:1178-79.

Dyer RA. Ceropegia, Brachystelma and Riocreuxia in South Africa. 1983.

Ceropegia concanensis, a new species (Apocynaceae: Ceropegieae) from Western Ghats, India. Kew Bull. 67:843-48.

Tomic JL, Pensalfini A, Head E, Glabe CG. Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction. Neurobiol Dis. 2009;35(3):352-58. https://doi.org/10.1016/j.nbd.2009.05.024

Yen GC, Duh PD. Scavenging effect of methanolic extracts of peanut hulls on free-radical and active oxygen species. J Agric Food Chem.1994;42: 629–32.

Published

01-07-2021

How to Cite

1.
Nayak SS, Mirgane NA, Pathade KB, Shivankar VS, Wadhawa GC. Phytochemical analysis, antioxidant and anti-inflammatory activity of leaves and bark of Ceropegia rollae Hemadri. Plant Sci. Today [Internet]. 2021 Jul. 1 [cited 2024 Nov. 21];8(3):425–428. Available from: https://horizonepublishing.com/journals/index.php/PST/article/view/906

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Research communications

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