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Research Articles

Vol. 13 No. 3 (2026)

Comprehensive analysis of antioxidants in Myrica nagi in India: Evidence and meta-analytic approach

DOI
https://doi.org/10.14719/pst.13203
Submitted
14 December 2025
Published
19-06-2026 — Updated on 01-07-2026
Versions

Abstract

Myrica nagi, also called Myrica esculenta, is an unrecognised fruit-bearing plant that grows wild in the Indian Himalayas. For generations, local communities used M. nagi in traditional medicine. Research shows that it is abundant in antioxidants, mainly due to high levels of phenolic and flavonoid content. This meta-analysis aims to investigate recent work done in India on the ability of Myrica to fight oxidative stress. The evidence is drawn from both in vitro and limited in vivo studies, focusing on various plant parts and extraction solvents. This study evaluates the feasibility of combining previous findings while identifying methodological differences, inconsistent data reporting and missing information. The findings consistently demonstrate substantial antioxidant activity, particularly in methanolic and polar extracts rich in phenolic and flavonoid compounds. Nevertheless, inconsistencies in outcome units (IC₅₀, % inhibition, Trolox equivalents), incomplete variance reporting and limited standardisation preclude reliable pooled effect size estimation at present. This review highlights the therapeutic promise of M. nagi while outlining essential methodological standardisation required for future quantitative meta-analysis and translational development.

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