The Indo-Gangetic Plains (IGP) account for nearly 75 % of India’s wheat production; however, more than 40 % of farmers in the region practice delayed sowing of wheat, resulting in substantial yield reductions. The research aim were to develop the genetic coefficient parameters and calibrate the model under late sown wheat growing region of IGP, in India. Decision support system for agrotechnology transfer (DSSAT) is a comprehensive software platform for the crop environment resource synthesis (CERES) wheat model. The CERES wheat model has been simulating crop growth and development in response to climate, soil, genotypes and management at various temporal and spatial scales. The required files of the model was prepared using the input data such as daily weather data, soil characteristics, crop management, crop phenology and productivity. The genetic coefficient codes were developed through the trail and error approach. The CERES wheat model was calibrated with two years data (i.e., 2008–2009 and 2009–2010) and validated through a separate data of 7 years long-term field experimental trail from 2011–12 to 2017–18. The model’s performance was evaluated using difference statistical indices i.e., root mean squared error (RMSE), normalised root mean squared error (NRMSE), mean absolute error (MAE) and D-index. Crop phenology (appearance of anthesis days and physiological maturity days) and productivity variables (grain yield and straw yield) were simulated using the calibrated model. The model effectively simulated trends in phenological stages namely appearance of anthesis days, physiological maturity, grain yield and straw yield for wheat cultivars i.e. HUW 243, HUW 510, Kundan and PBW 373. The values across all variables were indicated excellent agreement between simulated and observed data with deviations of less than 5 %, except for straw yield 9.15 %. The successfully calibrated model and the developed genetic coefficients provide a reliable tool for assessing the impact of environmental factors on late-sown wheat production in the region.