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Early Access

Chemical profiling of Rosa webbiana Wall. ex Royle from Kargil-UT Ladakh, using gas chromatography-mass spectrometry

DOI
https://doi.org/10.14719/pst.15198
Submitted
23 April 2026
Published
04-08-2026
Versions

Abstract

Rosa webbiana Wall. ex Royle is a medicinally important plant native to the western Himalayan region. Traditionally, it has been used to treat various ailments such as headaches, nerve pain, earaches, nasal swelling and bleeding, liver disorders, hepatitis and jaundice, as well as kidney, lung, heart and general health conditions. The plant is widely known to exhibit antioxidant, anti-inflammatory, antibacterial and neuroprotective effects. This study aimed to perform phytochemical profiling of the flowers and fruits of R. webbiana using gas chromatography-mass spectrometry (GC-MS). The flower and fruit of the plant were extracted using chloroform and methanol as solvents and analysed by GC-MS. The analysis revealed 78 and 34 compounds in the chloroform and methanol flower extracts and 64 and 24 compounds in the chloroform and methanol fruit extracts respectively. Major bioactive constituents included 5-hydroxymethylfurfuryl(35.93 %), reported to exhibit antioxidant and antiepileptic effects; and 4H-Pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl- (34.95 %), with antioxidant, antimicrobial, antiproliferative and anti-inflammatory activity. This study provides the first comprehensive phytochemical profiling of R. webbiana. The GC-MS analysis of flower and fruit extracts revealed the presence of many phytocompounds with known bioactivities. These findings highlight the plant's potential therapeutic relevance; however, further investigations are necessary to confirm the pharmacological properties and assess the safety and efficacy of the identified compounds.

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