Herbal Allies for Rheumatoid Arthritis: A Comprehensive Review of Natural Products

Ankita Singh; Madhu Kaushik; Swati Sinha; Ravindra Kumar Kachhap Oraon; Narotam Sharma; Indra Rautela

doi:10.14719/pst.2569

Authors

Ankita Singh Department of Biotechnology, School of Applied and Life Sciences (SALS), Uttaranchal University, Dehradun- 248007,Uttarakhand, INDIA. https://orcid.org/0000-0002-7011-6012
Madhu Kaushik Department of Biotechnology, School of Applied and Life Sciences (SALS), Uttaranchal University, Dehradun- 248007,Uttarakhand, INDIA. https://orcid.org/0009-0007-1055-0523
Swati Sinha Department of Biotechnology, School of Applied and Life Sciences (SALS), Uttaranchal University, Dehradun- 248007,Uttarakhand, INDIA. https://orcid.org/0009-0005-4445-0227
Ravindra Kumar Kachhap Oraon Department of Biotechnology, School of Applied and Life Sciences (SALS), Uttaranchal University, Dehradun- 248007,Uttarakhand, INDIA. https://orcid.org/0000-0002-2087-558X
Narotam Sharma DNA Labs- A Centre for Applied Sciences, Dehradun-248007, Uttarakhand, INDIA. https://orcid.org/0000-0003-0103-2322
Indra Rautela Department of Biotechnology, School of Applied and Life Sciences (SALS), Uttaranchal University, Dehradun- 248007,Uttarakhand, INDIA https://orcid.org/0000-0002-2159-7542

DOI:

https://doi.org/10.14719/pst.2569

Keywords:

Rheumatoid Arthritis, Natural products, Photoactive compounds, anti-inflammatory and anti-arthritic effects

Abstract

Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting primarily the joints, producing discomfort, inflammation, and potentially damaging joint destruction. Rheumatoid arthritis affects people all around the world, and its prevalence and impact differ by place. The World Health Organisation (WHO) estimates that 0.5% to 1% of the global population has rheumatoid arthritis. To decrease the progression of rheumatoid arthritis, disease-modifying anti-rheumatic medications (DMARDs) such as methotrexate and sulfasalazine are used. TNF inhibitors and IL-6 inhibitors are two examples of biologic DMARDs that target specific immune system components. Nonsteroidal anti-inflammatory drugs (NSAIDs) and analgesics help manage pain and inflammation while corticosteroids provide short-term relief during flares. Treatment strategies are tailored to the individual, and talking with a healthcare expert is essential for effective management. Herbal therapies are regarded to offer an advantage over synthetic pharmaceuticals for the treatment of rheumatoid arthritis due to their natural approach, potential symptom relief, holistic approach to health, and individualised therapy possibilities. However, scientific data supporting their effectiveness is sparse and variable, and their quality and safety can vary. Before adopting herbal therapies as part of a treatment plan, it is critical to check with a healthcare expert. Because of their natural chemicals with anti-inflammatory and analgesic characteristics, medicinal herbs may aid rheumatoid arthritis. However, further research is required to determine their efficacy, safety, and appropriate application.

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