Spectral analyses of fresh and dry Hypericum perforatum L. Effects with colloidal nano silver 30 ppm
DOI:
https://doi.org/10.14719/pst.1429Abstract
Spectral analyses of 1% water extracts of fresh and dry Hypericum perforatum L. and 1% dry H. perforatum with colloidal nano silver (NSPs) 30 ppm were conducted. The nano silver is standardised and patented by the Swiss company Evodrop. Non-equliblrium energy spectrum (NES) and Differential non-equliblrium energy spectrum (DNES) methods were used for the spectral analysis. A comparative analysis of 1% extracts of fresh and dry H. perforatum was performed in order to determine the local extremums for effects of nerve tissue conductivity at (-0.1112) eV, anti-inflammatory (-0.1212) eV, anti-tumor effects (-0.1387) eV. The results showed stimulating effect on the nervous system and improvement of nerve conduction (local extremums E=-0.1112 eV)(?=11.15 ?m) (?=897 cm-1), as well as anti-inflammatory effect (E = -0.1212 eV)( ?=10.23 ?m) (?=978 cm-1) and inhibition of development of tumor cells at a molecular level (E=-0.1387 eV) (?=8.95 ?m) (?=1117 cm-1). It was found that clusters of 16 and 15 water molecules are formed in the water herbal extracts of fresh H. perforatum and of dry H. perforatum with AgNPs 30 ppm. The fresh plant showed better results then the dry one. The addition of colloidal nano silver 30 ppm led to better results of the drug.
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Nestieva I, Valcheva-Kuzmanova S. Investigation of the variety and use of herbal antidepressants containing St. John’s Wort (Hypericum perforatum) in Bulgaria for the period 2014–2016. Health Economics and Management. 2017;63(1):30-36 (in Bulgarian) https://doi.org/10.14748/hem.v63i1.4716
Staneva D, Panova D, Raynova L, Assenov I. Herbs in Every Home, Medicine and Physical Education, Sofia, 1982. p. 38-39 (in Bulgarian).
Belwal T, Devkota HP, Singh MK, Sharma R, Upadhayay S, Joshi C, Bisht K, Gour JK, Bhatt ID, Rawal RS, Pande V. St. John’s Wort (Hypericum perforatum), Chapter 3.40, Nonvitamin and Nonmineral Nutritional Supplements, Elsevier. 2018. p. 415-32. https://doi.org/10.1016/B978-0-12-812491-8.00056-4
EMEA. EMA/HMPC/244315/2016, Committee on Herbal Medicinal Products (HMPC), Assessment report on Hypericum perforatum L., herba, Draft Based on Article 10a of Directive 2001/83/EC as amended (well-established use). 30 Jan 2018.
Imreova ?, Miadokova E, Galova E, Chankova S, Chalupa I. ?otential anticlastogenic effect of hyperforin, Mil Med Sci Lett (Voj. Zdrav. Listy). 2013;82(4):180-84. https://doi.org/10.31482/mmsl.2013.028
Milosevic T, Solujic S, Sukdolak S. In vitro study of ethanolic extract of Hypericum perforatum L. on growth and sporulation of some bacteria and fungi, Turk J Biol. 2007;31:237-41.
Karak P. ?iological activities of flavonoids: an overview. Int J Pharm Sci Res. 2019;10(4):1567-74.
Pato?ka J. The chemistry, pharmacology and toxicology of the biologically active constituents of the herb Hypericum perforatum L. J Appl Biomed. 2003;1:61–70, https://doi.org/10.32725/jab.2003.010
Klemow KM, Bartlow A, Crawford J, Kocher N, Shah J, Ritsick M. Medical Attributes of St. John’s Wort (Hypericum perforatum), Chapter 11, In: Herbal Medicine: Biomolecular and Clinical Aspects, 2nd, ed. Publisher: Boca Raton (FL): CRC Press/Taylor & Francis; Editors: Iris F. F. Benzie, Sissi Wachtel-Galor. 2011, https://doi.org/10.1201/b10787-12
Weber ND, Murray BK, North JA, Wood SG. The antiviral agent hypericin has in vitro activity against HSV-1 through non-specific association with viral and cellular membranes, Antivir Chem Chemother. 1994;5(2):83-90, https://doi.org/10.1177/095632029400500204
Ignatov I, Mosin OV. Structural Mathematical Models Describing Water Clusters, Journal of Mathematical Theory and Modeling. 2013;3(11):72-87.
Ignatov I, Gluhchev G, Neshev N, Mehandjiev D. Structuring of water clusters depending on the energy of hydrogen bonds in electrochemically activated waters Anolyte and Catholyte. Bulg Chem Commun. 2021;53(2):234-39.
Antonov A. Research of the Non-equilibrium Processes in the Area in Allocated Systems. Dissertation thesis for PhD, Blagoevgrad, Sofia. 1995.
Antonov A, Yusskesseliva L, Teodossieva I. Influence of ions on the structure of water under conditions far away from equilibrium. Physiology. 1989;26(4):255–60.
Al-Shmgani HS, Mohammed WH, Sulaiman GM, Saadoon AH. Biosynthesis of silver nanoparticles from Catharanthus roseus leaf extract and assessing their antioxidant, antimicrobial, and wound-healing activities. Artif Cells Nanomed Biotechnol. 2017;45:1234–1240, https://doi.org/10.1080/21691401.2016.1220950
Tododrov S, Damianova A, Sivriev I, Antonov A, Galabova T. Water energy spectrum method and investigation of the variations of the H-bond structure of natural waters. C R Acad Bulg Sci. 2008;61(7):857–62.
Appapalam ST, Panchamoorthy R. Aerva lanata mediated phytofabrication of silver nanoparticles and evaluation of their antibacterial activity against wound associated bacteria. J Taiwan Inst Chem Eng. 2017;78:539–51. https://doi.org/10.1016/j.jtice.2017.06.035
Ignatov I, Popova T. Applications of Moringa oleifera Lam., Urtica dioica L., Malva sylvestris L. and Plantago major L. Containing potassium for recovery. Plant Cell Biotechnol Mol Biol J. 2021;22(7-8):93-103.
Ignatov I, Popova T, Yaneva I, Balabanski V, Baiti S, Angelcheva M, Angushev I. Spectral analysis of Sambucus nigra L. fruits and flowers for elucidation of their analgesic, diuretic, anti-inflammatory and anti-tumor effects. Plant Cell Biotechnol Mol Biol J. 2021;22(29-30):134-40.
Al-Shmgani HS, Mohammed WH, Sulaiman GM, Saadoon AH. Biosynthesis of silver nanoparticles from Catharanthus roseus leaf extract and assessing their antioxidant, antimicrobial and wound-healing activities. Artif Cells Nanomed Biotechnol. 2017;45:1234–40. https://doi.org/10.1080/21691401.2016.1220950
Appapalam ST, Panchamoorthy R. Aerva lanata mediated phytofabrication of silver nanoparticles and evaluation of their antibacterial activity against wound associated bacteria. J Taiwan Inst Chem Eng. 2017;78:539–51. https://doi.org/10.1016/j.jtice.2017.06.035
Arunachalam KD, Annamalai SK, Arunachalam AM, Kennedy S. Green synthesis of crystalline silver nanoparticles using Indigofera aspalathoides medicinal plant extract for wound healing applications. Asian J Chem. 2013;25:311–14.
Beg M, Maji A, Mandal AK, Das S, Jha PK, Hossain M. Spectroscopic investigation on interaction of biogenic, Croton bonplandianum leaves extract mediated potential bactericidal silver nanoparticles with human hemoglobin and human serum albumin. J Biomol Struct Dyn. 2017;36:711–23. https://doi.org/10.1080/07391102.2017.1294505
Bhagavathy S, Kancharla S. Wound healing and angiogenesis of silver nanoparticle from Azadirachta indica in diabetes induced mice. Int J Herb Med. 2016;4(5):24-29.
Chandran SP, Chaudhary M, Pasricha R, Ahmad A, Sastry M. Synthesis of gold nanotriangles and silver nanoparticles using Aloe vera plant extract. Biotechnol Prog. 2006;22:577–83. https://doi.org/10.1021/bp0501423
Emmanuel R, Saravanan M, Ovais M, Padmavathy S, Shinwari ZK, Prakash P. Antimicrobial efficacy of drug blended biosynthesized colloidal gold nanoparticles from Justicia glauca against oral pathogens: a nanoantibiotic approach. Microb Pathog. 2017;113:295–302, https://doi.org/10.1016/j.micpath.2017.10.055
Garg S, Chandra A, Mazumder A, Mazumder R. Green synthesis of silver nanoparticles using Arnebia nobilis root extract and wound healing potential of its hydrogel. Asian J Pharm. 2014;8:95–101, https://doi.org/10.4103/0973-8398.134925
Kasithevar M, Saravanan M, Prakash P, Kumar H, Ovais M, Barabadi H, Shinwari ZK. Green synthesis of silver nanoparticles using Alysicarpus monilifer leaf extract and its antibacterial activity against MRSA and CoNS isolates in HIV patients. J Interdiscip Nanomed. 2017;2:131–41. https://doi.org/10.1002/jin2.26
Shankar S, Jaiswal L, Aparna RSL, Prasad RGSV, Kumar GP, Manohara CM. Wound healing potential of green synthesized silver nanoparticles prepared from Lansium domesticum fruit peel extract. Mater Express. 2015;5:159–64. https://doi.org/10.1166/mex.2015.1225
Subbaiya R, Saravanan M, Priya AR, Shankar KR, Selvam M, Ovais M, Balajee R, Barabadi H. Biomimetic synthesis of silver nanoparticles from Streptomyces atrovirens and their potential anticancer activity against human breast cancer cells. IET Nanobiotechnol. 2017;11:965–72. https://doi.org/10.1049/iet-nbt.2016.0222
Venkatachalam P, Sangeetha P, Geetha N, Sahi SV. Phytofabrication of bioactive molecules encapsulated metallic silver nanoparticles from Cucumis sativus L. and its enhanced wound healing potential in rat model. J Nanomater. 2015;16:241–49. https://doi.org/10.1155/2015/753193
Zakharova OV. Sodium tallow amphopolycarboxyglycinate-stabilized silver nanoparticles suppress early and late blight of Solanum lycopersicum and stimulate the growth of tomato plants. Bio Nano Science. 2017;7, 692-702, https://doi.org/10.1007/s12668-017-0406-2
Popova T, Ignatov I. In vitro Antimicrobial activity of colloidal nano silver. Bulg J Vet Med. 2021. Online First. Available from: http://tru.uni-sz.bg/bjvm/2411%20Popova%20&%20Ignatov%20OnFirst.pdf
Valcheva N, Ignatov I, Huether F. Microbiological research of the effects of EVODROP silver nanoparticle on Escherichia coli, Enterococci and Coliforms. Journal of Advances in Microbiology. 2020;20(11):22-31. https://doi.org/10.9734/jamb/2020/v20i1130297
Popova, T. P., I. Ignatov, F. Huether, T. Petrova. Antimicrobial activity of colloidal nanosilver 24 ppm in vitro. Bulgarian Chemical Communications, 53, 3, 365 – 70, 2021. DOI: 10.34049/bcc.53.3.5404.
Chimshirova R, Karsheva M, Diankov S, Hinkov I. ?xtraction of valuable compounds from bulgarian St. John’s wort (Hypericum perforatum L.) antioxidant capacity and total polyphenolic content. J Chem Technol Metall. 2019;54(5):952-61.
Isacchi ?, Bergonzi MC, Carnevali F, van der Esch SA, Vincieri FF, Bilia AR. Analysis and stability of the constituents of St. John’s wort oils prepared with different methods. J Pharm Biomed Anal. 2007; 45:756–61. https://doi.org/10.1016/j.jpba.2007.08.025
Franchi GG, Nencini C, Collavoli E, Massarelli P. Composition and antioxidant activity in vitro of different St. John’s Wort (Hypericum perforatum L.) extracts. J Med Plant Res. 2011;5(17):4349-53.
Zeliou ?, Kontaxis NI, Margianni E, Petrou C, Lamari FN. Optimized and validated HPLC analysis of St. John’s Wort extract and final products by simultaneous determination of major ingredients. J Chromatogr Sci. 2017;55(8): 805-12. https://doi.org/10.1093/chromsci/bmx040
Wernet P, Nordlund D, Bergmann U, Cavalleri M, Odelius M, Ogasawara H, Näslund LA, Hirsch TK, Ojamäe L, Glatzel P, Pettersson LG, Nilsson A. The structure of the first coordination shell in liquid water. Science. 2004;304:995–99. https://doi.org/10.1126/science.1096205
Yang L, Ji H, Liu X, Lu WC. Ring-stacking water clusters: Morphology and Stabilities. ChemistryOpen. 2019;8(2):210-18. https://doi.org/10.1002/open.201800284
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