A review of Parthenium management: Transforming a troubling weed into a therapeutic medicinal plant

T Abhinaya; K Thirukumaran; R Karthikeyan; G S Prabukumar; R  Sivakumar; P Dhananchezhiyan; V Sampathrajan; P Parasuraman; S A Aravind; V Saitheja

doi:10.14719/pst.4733

Authors

T Abhinaya Department of Agronomy, Tamil Nadu Agricultural University, Coimbatore 641 003, India https://orcid.org/0009-0009-5406-1785
K Thirukumaran Department of Agronomy, Tamil Nadu Agricultural University, Coimbatore 641 003, India https://orcid.org/0000-0002-2302-9856
R Karthikeyan Directorate of Crop Management (DCM), Tamil Nadu Agricultural University, Coimbatore 641 003, India https://orcid.org/0000-0002-6786-5899
G S Prabukumar Department of Agronomy, Tamil Nadu Agricultural University, Coimbatore 641 003, India https://orcid.org/0000-0003-4214-980X
R Sivakumar Directorate of Crop Management (DCM), Tamil Nadu Agricultural University, Coimbatore 641 003, India https://orcid.org/0000-0001-6941-9940
P Dhananchezhiyan Department of Farm Machinery and Power Engineering, Tamil Nadu Agricultural University, Coimbatore 641 003, India https://orcid.org/0000-0002-8167-5602
V Sampathrajan Department of Biochemistry, Tamil Nadu Agricultural University, Coimbatore 641 003, India https://orcid.org/0000-0001-9277-457X
P Parasuraman Department of Agronomy, Tamil Nadu Agricultural University, Coimbatore 641 003, India https://orcid.org/0000-0003-1903-2806
S A Aravind Department of Agronomy, Tamil Nadu Agricultural University, Coimbatore 641 003, India https://orcid.org/0000-0003-1920-4639
V Saitheja Department of Agronomy, Tamil Nadu Agricultural University, Coimbatore 641 003, India https://orcid.org/0009-0001-4211-0211

DOI:

https://doi.org/10.14719/pst.4733

Keywords:

active compounds, β-sitosterol, hypoglycemic effect, pharmacological uses

Abstract

Parthenium hysterophorus L., an invasive plant species, has proliferated globally beyond its native distribution, exacerbating ecological challenges. Traditionally, plants have been an integral part of medicinal practices, particularly in less industrialized countries, where herbal remedies are costeffective alternatives to modern pharmaceuticals. The management of invasive weeds like P. hysterophorus involves various methods; however, its medicinal potential, particularly for addressing diabetes, could also be explored. Contrary to conventional intervention methods such as physical, chemical, or biological controls, this review advocates exploring Parthenium's medicinal applications. Phytochemical and medicinal assessments reveal the plant's efficacy against a spectrum of health concerns, including antimicrobial, anti-anemic, antipyretic, anticancer, antioxidant, lipoprotective, hypoglycemic and hepatoprotective properties. Diabetes mellitus, impacting approximately 1.5% of the global population, remains a pervasive and enduring metabolic condition, posing a substantial global health challenge. In India, in regions like Maharashtra and Gujarat, P. hysterophorus weeds are being used to treat diabetes mellitus. The plant's extensive medicinal uses suggest its potential in preventive measures against various diseases, positioning it as a valuable asset in the development of future medications. This review underscores the importance of shifting from conventional weed management strategies to exploring the untapped medicinal potential of invasive species like P. hysterophorus, offering a dual benefit of environmental conservation and medical advancements.

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